Gupta Ashok K, Gupta Karan, Sunku Satheesh K, Modi Manish, Gupta Amod
Department of Otolaryngology, Head & Neck Surgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Department of Otolaryngology, Head & Neck Surgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Int J Pediatr Otorhinolaryngol. 2014 Oct;78(10):1686-91. doi: 10.1016/j.ijporl.2014.07.019. Epub 2014 Jul 22.
To assess the effectiveness of transnasal trans-sphenoid endoscopic optic nerve fenestration for the reversal of vision loss in pediatric idiopathic intracranial hypertension (IIH).
This is a single center observational retrospective case series. Fifteen diagnosed pediatric patients of IIH satisfying the modified Dandy criteria and reported to the out-patient services of otolaryngology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India were included in this study. All children underwent thorough clinical examination, complete neuro-ophthalmological work up including visual acuity (V/A), visual field charting(V/F), fundus venogram and radiological work up with MRI for special optic nerve sections in sagittal reconstruction. cerebro-spinal fluid pressure (CSF) measured pre operatively for all children. Standard endoscopic optic nerve sheath fenestration was performed on all children. Visual improvement was assessed by comparing pre-operative ophthalmological findings.
Improvement in vision was taken as a positive outcome. Vision improved in all except two children, who had pre-existing optic nerve atrophy.
Endoscopic optic nerve fenestration is an effective minimally invasive procedure to revert visual loss in pediatric Idiopathic Intracranial Hypertension.
评估经鼻蝶窦内镜视神经开窗术对小儿特发性颅内高压(IIH)所致视力丧失恢复的有效性。
这是一项单中心观察性回顾性病例系列研究。本研究纳入了15例符合改良丹迪标准、在印度昌迪加尔医学教育与研究研究生院(PGIMER)耳鼻喉科门诊就诊的确诊小儿IIH患者。所有患儿均接受了全面的临床检查、完整的神经眼科检查,包括视力(V/A)、视野检查(V/F)、眼底静脉造影以及针对矢状面重建的特殊视神经节段的MRI影像学检查。所有患儿术前均测量了脑脊液压力(CSF)。对所有患儿均实施了标准的内镜视神经鞘开窗术。通过比较术前眼科检查结果评估视力改善情况。
视力改善被视为阳性结果。除两名已有视神经萎缩的患儿外,其他所有患儿的视力均有改善。
内镜视神经开窗术是一种有效的微创手术,可恢复小儿特发性颅内高压所致的视力丧失。