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鼻内镜下经鼻治疗良性颅内压增高症:有效吗?

Endoscopic endonasal management of pseudotumor cerebri: is it effective?

作者信息

Gupta Ashok K, Gupta Anish, Kumar Sudesh, Lal Vivek

机构信息

Department of ENT, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Laryngoscope. 2007 Jul;117(7):1138-42. doi: 10.1097/MLG.0b013e31805c9a7a.

Abstract

PURPOSE

To study the efficacy and safety of endoscopic endonasal optic nerve fenestration for the management of idiopathic intracranial hypertension (IIH).

DESIGN

A prospective study at a tertiary care center.

PATIENTS AND METHODS

All patients with a final diagnosis of IIH from July 2001 to March 2005 were included and subjected to detailed neuro-ophthalmologic examination and endoscopic endonasal optic nerve fenestration. Postoperative visual acuity and the perimetry was compared with the preoperative status, and the results were analyzed using the chi2 test.

RESULTS

: Of the 18 patients included in the study, 17 had improvement in vision postoperatively. Fifteen patients had visual deterioration in the other eye as well, and of these, 12 had improvement, obviating the need for surgery on the other side. Complications were minimal and in the form of synechiae in two of the cases.

DISCUSSION

A number of procedures have been described for the management of this entity, and each is associated with a significant morbidity; therefore, there was a need for a minimally invasive procedure. The procedure adopted in the series is minimally invasive and is associated with a 94.5% success rate and minimal morbidity.

CONCLUSIONS

Endoscopic endonasal optic nerve fenestration is a safe, minimally invasive, and extremely effective procedure for the management of IIH.

摘要

目的

研究鼻内镜下视神经开窗术治疗特发性颅内高压(IIH)的疗效和安全性。

设计

在一家三级医疗中心进行的前瞻性研究。

患者和方法

纳入2001年7月至2005年3月最终诊断为IIH的所有患者,对其进行详细的神经眼科检查及鼻内镜下视神经开窗术。将术后视力和视野与术前情况进行比较,并采用卡方检验分析结果。

结果

该研究纳入的18例患者中,17例术后视力改善。15例患者对侧眼也有视力下降,其中12例视力改善,无需对侧眼手术。并发症极少,2例出现粘连。

讨论

针对该疾病已描述了多种治疗方法,每种方法都有较高的发病率;因此,需要一种微创手术。本系列采用的手术为微创手术,成功率为94.5%,发病率极低。

结论

鼻内镜下视神经开窗术是治疗IIH的一种安全、微创且极其有效的方法。

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