Eslani Medi, Baradaran-Rafii Alireza, Movahedan Asadolah, Djalilian Ali R
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA.
Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Ophthalmol. 2014;2014:196827. doi: 10.1155/2014/196827. Epub 2014 Jul 1.
Ocular chemical burns are common and serious ocular emergencies that require immediate and intensive evaluation and care. The victims of such incidents are usually young, and therefore loss of vision and disfigurement could dramatically affect their lives. The clinical course can be divided into immediate, acute, early, and late reparative phases. The degree of limbal, corneal, and conjunctival involvement at the time of injury is critically associated with prognosis. The treatment starts with simple but vision saving steps and is continued with complicated surgical procedures later in the course of the disease. The goal of treatment is to restore the normal ocular surface anatomy and function. Limbal stem cell transplantation, amniotic membrane transplantation, and ultimately keratoprosthesis may be indicated depending on the patients' needs.
眼部化学伤是常见且严重的眼部急症,需要立即进行全面评估和精心护理。此类事故的受害者通常较为年轻,因此视力丧失和容貌损毁会极大地影响他们的生活。临床过程可分为即刻期、急性期、早期和晚期修复期。受伤时角膜缘、角膜和结膜的受累程度与预后密切相关。治疗从简单但能挽救视力的步骤开始,后期在病程中还会进行复杂的外科手术。治疗的目标是恢复正常的眼表解剖结构和功能。根据患者需求,可能需要进行角膜缘干细胞移植、羊膜移植,最终可能需要进行角膜移植术。