Francis Donald P, Du Yu-Ping, Precioso Alexander R
Global Solutions for Infectious Diseases, South San Francisco, CA, USA.
Vaccine Consultant, Beijing, PR China; Former WHO Medical Officer, EPI, Democratic People's Republic of Korea.
Vaccine. 2014 Sep 15;32(41):5259-65. doi: 10.1016/j.vaccine.2014.07.069. Epub 2014 Aug 8.
Hallmarks in the remarkable evolution of vaccines and their application include the eradication of smallpox, the development and delivery of the early childhood vaccines and the emergence of recombinant vaccines initiated by the hepatitis B vaccine. Now we enter a most exciting era as vaccines are increasingly produced and delivered in less developed countries. The results are dramatic decreases in childhood morbidity and mortality around the world.
疫苗显著发展历程及其应用的标志包括天花的根除、儿童早期疫苗的研发与推广,以及由乙肝疫苗引领的重组疫苗的出现。如今,随着疫苗在欠发达国家的生产与供应日益增多,我们步入了一个极为激动人心的时代。其结果是全球儿童发病率和死亡率大幅下降。