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多源相控射频治疗亚洲人皮肤松弛:三维可视化皮肤紧致效果及组织学研究显示弹性蛋白密度增加

Treatment of skin laxity using multisource, phase-controlled radiofrequency in Asians: visualized 3-dimensional skin tightening results and increase in elastin density shown through histologic investigation.

作者信息

Tanaka Yohei, Tsunemi Yuichiro, Kawashima Makoto, Tatewaki Naoto, Nishida Hiroshi

机构信息

*Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, Matsumoto, Nagano, Japan; †Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan; ‡Department of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan.

出版信息

Dermatol Surg. 2014 Jul;40(7):756-62. doi: 10.1111/dsu.0000000000000047.

Abstract

BACKGROUND

A new multisource phase-controlled radiofrequency (MPCRF) device is widely used for skin tightening and rejuvenation in Asia.

OBJECTIVE

To evaluate the efficacy of MPCRF objectively and histologically.

METHODS

An MPCRF device with real-time impedance control was evaluated. Ten Japanese patients were treated one side of the face, and the untreated side served as a control. Three-dimensional (3-D) imaging was performed to evaluate the posttreatment volume change. An independent observer assessed the 3-D images. Histologic evaluations of elastin were performed by Victoria Blue staining in 5 Japanese patients.

RESULTS

Objective assessments evaluated by a 3-D color schematic representation showed improvement in skin laxity after the final treatment in all patients. The treated side improved markedly compared with the untreated side; however, even the untreated side slightly improved. The elastin density was significantly increased compared with controls in all 5 Japanese patients (p = .0013). Induced elastin appeared to be relatively thin elastic fibers without irregular elastic fibers, such as solar elastosis. Side effects were not observed, and the patients reported feeling comfortable throughout the study.

CONCLUSION

Multisource phase-controlled radiofrequency treatments provide stimulation of elastin and skin-tightening results safely and effectively, and thus are beneficial for improving skin laxity and rhytides.

摘要

背景

一种新型多源相位控制射频(MPCRF)设备在亚洲被广泛用于皮肤紧致和年轻化治疗。

目的

从客观和组织学角度评估MPCRF的疗效。

方法

对一种具有实时阻抗控制的MPCRF设备进行评估。10名日本患者一侧面部接受治疗,未治疗的一侧作为对照。采用三维(3-D)成像评估治疗后的体积变化。由一名独立观察者评估3-D图像。对5名日本患者进行维多利亚蓝染色,对弹性蛋白进行组织学评估。

结果

通过三维彩色示意图进行的客观评估显示,所有患者在最终治疗后皮肤松弛情况均有改善。治疗侧与未治疗侧相比有明显改善;然而,即使是未治疗侧也有轻微改善。在所有5名日本患者中,弹性蛋白密度与对照组相比显著增加(p = 0.0013)。诱导产生的弹性蛋白似乎是相对较细的弹性纤维,没有不规则的弹性纤维,如日光性弹性组织变性。未观察到副作用,患者在整个研究过程中均表示感觉舒适。

结论

多源相位控制射频治疗能安全有效地刺激弹性蛋白生成并产生皮肤紧致效果,因此有利于改善皮肤松弛和皱纹。

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