Kwon Hyuck Hoon, Lee Won-Yong, Choi Sun Chul, Jung Jae Yoon, Bae Youin, Park Gyeong-Hun
a Oaro Dermatology Clinic , Seoul , Korea.
b Seoul Institute of Clinical Cosmetology , Seoul , Korea.
J Cosmet Laser Ther. 2018 Nov-Dec;20(7-8):449-453. doi: 10.1080/14764172.2018.1427870. Epub 2018 Feb 22.
Although various minimal invasive approaches are available for aging skin laxity, they alone may not lead to notably satisfactory results.
To evaluate the effectiveness and safety of combination regimen with monopolar radiofrequency (MRF) and intense-focused ultrasound (IFUS) in facial lifting and tightening.
Twenty-two Korean participants with aging face received a sequential single session of MRF and IFUS treatment. Objective and subjective assessments for improvement were performed at the 20-week post-treatment. Safety profiles were also recorded, and skin biopsies were taken at baseline and follow-up visit.
Based on the objective assessment for the overall facial skin tightening and laxity, 19 patients (90%) demonstrated "moderate" or better improvements (more than 25%) compared with baseline. Specifically, improvements of skin laxity and sagging, and droopy jaw line were more noticeable compared with that of superficial skin texture (P < 0.05). Subjective satisfactions were generally consistent with objective findings, and no serious adverse effect was observed. Histologic evaluation showed increased dermal collagen fibers throughout the dermis after treatments (P < 0.05).
Combination treatment of MRF and IFUS has cumulative benefits for skin lifting and tightening with satisfactory safety profiles in Asian subjects.
尽管有多种微创方法可用于改善皮肤松弛，但这些方法单独使用可能无法取得特别令人满意的效果。
评估单极射频（MRF）联合高强度聚焦超声（IFUS）对面部提升紧致的有效性和安全性。
22名面部老化的韩国参与者接受了单极射频和高强度聚焦超声的序贯单次治疗。在治疗后20周进行改善情况的客观和主观评估。记录安全性情况，并在基线和随访时取皮肤活检样本。
基于对面部整体皮肤紧致度和松弛度的客观评估，与基线相比，19名患者（90%）表现出“中度”或更好的改善（超过25%）。具体而言，与浅表皮肤质地相比，皮肤松弛、下垂以及下颌轮廓下垂的改善更为明显（P < 0.05）。主观满意度与客观结果总体一致，未观察到严重不良反应。组织学评估显示治疗后整个真皮层的真皮胶原纤维增加（P < 0.05）。
单极射频联合高强度聚焦超声的联合治疗对亚洲受试者的皮肤提升紧致具有累积益处，且安全性良好。
