Milstein J M, Geyer J R, Berger M S, Bleyer W A
Children's Hospital and Medical Center, University of Washington School of Medicine, Seattle.
J Neurooncol. 1989 Nov;7(4):367-71. doi: 10.1007/BF02147094.
Over a two year interval, we have treated five children with neurofibromatosis who developed brainstem gliomas. They had an insidious onset of symptoms and other indicators of low grade tumor despite several features that have been ascribed to rapidly progressive brainstem gliomas. Following standard radiation therapy a more protracted improvement was observed with the persistence of preradiation findings for several months. This experience confirms the better prognosis in brainstem glioma associated with neurofibromatosis.
在两年的时间里，我们治疗了5名患有神经纤维瘤病且患上脑干胶质瘤的儿童。尽管他们有一些被认为是快速进展性脑干胶质瘤的特征，但症状隐匿，且有低度肿瘤的其他指标。在进行标准放疗后，观察到病情有更持久的改善，放疗前的症状持续了几个月。这一经验证实了与神经纤维瘤病相关的脑干胶质瘤预后较好。
