Saeki Harumi, Suzuki Chikako, Yamasaki Shigetaka, Hashizume Akane, Izumi Hiroshi, Suzuki Fujihiko, Ishi Kazuhisa, Nojima Michio, Hino Okio
School of Medicine, Department of Pathology and Oncology, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan,
Arch Gynecol Obstet. 2015 Feb;291(2):357-61. doi: 10.1007/s00404-014-3406-2. Epub 2014 Aug 13.
Cotyledonoid dissecting leiomyoma (Sternberg tumor) is a rare variant of the uterine smooth muscle tumor. Although this tumor is a benign tumor clinically and pathologically, the appearance and growth pattern is unusual, so it may be misdiagnosed as malignancy.
We report two cases of cotyledonoid dissecting leiomyoma of the uterus that occurred in two 44- and 31-year-old women, respectively. Total hysterectomy and bilateral salpingo-oophorectomy were performed in one of the patients, and myomectomy was done in the other one. Macroscopically, both tumors were grape-like exophytic masses resembling placental tissue. The patients were well after surgery, and one patient gave birth. To our knowledge, this is the first case report of a successful delivery after myomectomy of this tumor.
To prevent aggressive surgery it is important to recognize that this tumor is a benign and unusual appearing variant of leiomyoma. A fertility-sparing surgical procedure should be considered if the patient wishes to preserve her fertility.
子叶状分割性平滑肌瘤(斯特恩伯格瘤)是子宫平滑肌瘤的一种罕见变体。尽管该肿瘤在临床和病理上为良性肿瘤,但其外观和生长模式不寻常,因此可能被误诊为恶性肿瘤。
我们报告了两例子宫子叶状分割性平滑肌瘤,分别发生在两名44岁和31岁的女性身上。其中一名患者接受了全子宫切除术和双侧输卵管卵巢切除术,另一名患者接受了肌瘤切除术。宏观上,两个肿瘤均为葡萄样外生性肿块,类似胎盘组织。患者术后恢复良好,其中一名患者分娩。据我们所知,这是该肿瘤肌瘤切除术后成功分娩的首例病例报告。
为避免激进手术,认识到该肿瘤是一种良性且外观不寻常的平滑肌瘤变体很重要。如果患者希望保留生育能力,应考虑保留生育功能的手术方法。