Ivanov A I
Radiobiologiia. 1989 Sep-Oct;29(5):625-31.
Exposure of 3-hour drosophila male embryos to gamma-radiation during the topographic segregation of the germ anlage nuclei caused recessive sex-linked lethals in somatic cells only. The selectivity of the screening was determined by the ratio of mutation frequencies induced in embryos and adult males. Analysis of lethal mutations shows that a minimal rate of the divergence between germinal and somatic patterns of the cell development is observed in the embryogenesis, the 3d instar larva and prepupa, and maximal in the 1st and 2nd larva and pupa.
在生殖原基细胞核进行地形学分离期间，将3小时龄的果蝇雄性胚胎暴露于γ辐射下，结果仅在体细胞中诱发了隐性性连锁致死突变。筛选的选择性由胚胎和成体雄蝇中诱导的突变频率之比决定。对致死突变的分析表明，在胚胎发生、三龄幼虫和预蛹期，细胞发育的生殖细胞模式和体细胞模式之间的差异率最小，而在一龄和二龄幼虫以及蛹期差异率最大。
