Scapagnini Giovanni, Davinelli Sergio, Di Renzo Laura, De Lorenzo Antonino, Olarte Hector Hugo, Micali Giuseppe, Cicero Arrigo F, Gonzalez Salvador
Department of Medicine and Health Sciences, University of Molise, Campobasso 86100, Italy.
Division of Human Nutrition, Department of Neuroscience, University of Rome Tor Vergata, Rome 00173, Italy.
Nutrients. 2014 Aug 11;6(8):3202-13. doi: 10.3390/nu6083202.
Cocoa has a rich history in human use. Skin is prone to the development of several diseases, and the mechanisms in the pathogenesis of aged skin are still poorly understood. However, a growing body of evidence from clinical and bench research has begun to provide scientific validation for the use of cocoa-derived phytochemicals as an effective approach for skin protection. Although the specific molecular and cellular mechanisms of the beneficial actions of cocoa phytochemicals remain to be elucidated, this review will provide an overview of the current literature emphasizing potential cytoprotective pathways modulated by cocoa and its polyphenolic components. Moreover, we will summarize in vivo studies showing that bioactive compounds of cocoa may have a positive impact on skin health.
可可在人类的使用中有着悠久的历史。皮肤容易患上多种疾病，而衰老皮肤发病机制中的相关机理仍知之甚少。然而，临床和实验室研究中越来越多的证据已开始为使用可可衍生的植物化学物质作为一种有效的皮肤保护方法提供科学验证。尽管可可植物化学物质有益作用的具体分子和细胞机制仍有待阐明，但本综述将概述当前文献，重点介绍由可可及其多酚成分调节的潜在细胞保护途径。此外，我们将总结体内研究，这些研究表明可可的生物活性化合物可能对皮肤健康产生积极影响。
Zotero 插件