Fernández-Friera Leticia, Ibáñez Borja, Fuster Valentín
Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
J Cardiovasc Transl Res. 2014 Oct;7(7):623-34. doi: 10.1007/s12265-014-9582-4. Epub 2014 Aug 14.
Imaging subclinical atherosclerosis holds the promise of individualized cardiovascular (CV) risk assessment. The large arsenal of noninvasive imaging techniques available today is playing an increasingly important role in the diagnosis and monitoring of subclinical atherosclerosis. However, there is a debate about the advisability of clinical screens for subclinical atherosclerosis and which modality is the most appropriate for monitoring risk and atherosclerosis progression. This article offers an overview of the traditional and emerging noninvasive imaging modalities used to detect early atherosclerosis, surveys population studies addressing the value of subclinical atherosclerosis detection, and also examines guideline recommendations for their clinical implementation. The clinical relevance of this manuscript lies in the potential of current imaging technology to improve CV risk prediction based on traditional risk factors and the present recommendations for subclinical atherosclerosis assessment. Noninvasive imaging will also help to identify individuals at high CV who would benefit from intensive prevention or therapeutic interventions.
对亚临床动脉粥样硬化进行成像有望实现个性化的心血管（CV）风险评估。如今可用的大量非侵入性成像技术在亚临床动脉粥样硬化的诊断和监测中发挥着越来越重要的作用。然而，对于亚临床动脉粥样硬化临床筛查的可取性以及哪种方式最适合监测风险和动脉粥样硬化进展存在争议。本文概述了用于检测早期动脉粥样硬化的传统和新兴非侵入性成像方式，调查了探讨亚临床动脉粥样硬化检测价值的人群研究，并审视了其临床应用的指南建议。本手稿的临床意义在于当前成像技术基于传统风险因素改善CV风险预测的潜力以及目前亚临床动脉粥样硬化评估的建议。非侵入性成像还将有助于识别那些将从强化预防或治疗干预中受益的高CV风险个体。
