梅尔克森－罗森塔尔综合征和贝尔麻痹中的面神经麻痹：家族史和复发倾向。
Facial palsy in Melkersson-Rosenthal syndrome and Bell's palsy: familial history and recurrence tendency.
作者信息
Sun Baochun, Zhou Chengyong, Han Zeli
机构信息
Department of Otolaryngology, The First Affiliated Hospital of PLA General Hospital, Beijing, China.
Department of Otolaryngology, The First Affiliated Hospital of PLA General Hospital, Beijing, China
出版信息
Ann Otol Rhinol Laryngol. 2015 Feb;124(2):107-9. doi: 10.1177/0003489414546398. Epub 2014 Aug 13.
OBJECTIVE
The aim of this study was to compare genetic predilection and recurrence tendency between facial palsy in Melkersson-Rosenthal syndrome (MRS) and Bell's palsy
METHODS
We carried out an investigation on patients with facial palsy in MRS and those with Bell's palsy who visited the outpatient department in our hospital between February 2009 and February 2013. They were asked about familial history and whether it was the first episode, with the results recorded and compared.
RESULTS
There were 16 patients with facial palsy in MRS and 860 patients with Bell's palsy involved in the study. Familial history was positive in 5 of 16 patients (31.3%) with facial palsy in MRS and 56 of 860 patients (6.5%) with Bell's palsy (P < .01). Twelve of 16 cases (75%) with facial palsy in MRS and 88 of 860 cases (10.2%) with Bell's palsy had a history of facial palsy in the past (P < .01).
CONCLUSION
Compared to Bell's palsy, facial palsy in MRS has an obvious genetic predilection and recurrence tendency.
目的
本研究旨在比较梅尔克森 - 罗森塔尔综合征（MRS）所致面瘫与贝尔面瘫之间的遗传易感性和复发倾向。
方法
我们对2009年2月至2013年2月期间到我院门诊就诊的MRS所致面瘫患者和贝尔面瘫患者进行了调查。询问他们的家族史以及是否为首次发作，并记录结果进行比较。
结果
本研究纳入了16例MRS所致面瘫患者和860例贝尔面瘫患者。16例MRS所致面瘫患者中有5例（31.3%）家族史呈阳性，860例贝尔面瘫患者中有56例（6.5%）家族史呈阳性（P <.01）。16例MRS所致面瘫患者中有12例（75%）既往有面瘫病史，860例贝尔面瘫患者中有88例（10.2%）既往有面瘫病史（P <.01）。
结论
与贝尔面瘫相比，MRS所致面瘫具有明显的遗传易感性和复发倾向。
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