Singh Harminder, Kaur Kamalpreet, Banipal Raja Paramjeet Singh, Singh Shaminder, Bala Ritu
Department of Pharmacology, Guru Gobind Singh Medical College, Faridkot, Punjab, India ; Guru Gobind Singh Medical College, Faridkot, Punjab, India.
Guru Gobind Singh Medical College, Faridkot, Punjab, India ; Department of Radiotherapy and Oncology, Guru Gobind Singh Medical College, Faridkot, Punjab, India.
Indian J Palliat Care. 2014 May;20(2):116-22. doi: 10.4103/0973-1075.132627.
The objective of this prospective, non-interventional, 4-month observational study was to analyze and compare patient-reported quality of life (QOL) and their physical/psychosocial symptom burden during their respective chemotherapy sessions.
A prospective and descriptive study was carried out jointly by Pharmacology and Oncology Departments of a tertiary care center in Malwa region of Punjab. The data collection was performed by administering validated questionnaire/response after taking informed consent.
A total of 131 cancer patients were recruited with the mean age of 49.05 ± 14.35 (SD (standard deviation)) years. As per the QOL scoring of Global Health Status (GHS) and four items of symptom scale, that is, insomnia, pain, appetite loss, and constipation, and financial difficulties attained a significance difference. GHS significantly improved in group three as compared to group one, indicating that the patient's overall health/QOL improved as the chemotherapy session progressed.
Although QOL scoring system did not show significant improvement in all areas (except insomnia, pain, appetite loss, constipation, and financial difficulties) with reference to their respective chemotherapy cycles, but a judicious diagnosis with an appropriate treatment including chemotherapy may lessen the negative perception of cancer as a deadly and fatal disease in our rural population.
这项前瞻性、非干预性、为期4个月的观察性研究的目的是分析和比较患者报告的生活质量(QOL)及其在各自化疗疗程中的身体/心理社会症状负担。
旁遮普邦马尔瓦地区一家三级护理中心的药理学和肿瘤学部门联合开展了一项前瞻性描述性研究。在获得知情同意后,通过发放经过验证的问卷/进行询问来收集数据。
共招募了131名癌症患者,平均年龄为49.05±14.35(标准差)岁。根据全球健康状况(GHS)的生活质量评分以及症状量表的四个项目,即失眠、疼痛、食欲减退和便秘,以及经济困难方面存在显著差异。与第一组相比,第三组的GHS有显著改善,这表明随着化疗疗程的推进,患者的整体健康状况/生活质量得到了改善。
尽管生活质量评分系统在各自的化疗周期中,在所有领域(除失眠、疼痛、食欲减退、便秘和经济困难外)并未显示出显著改善,但通过包括化疗在内的适当治疗进行明智的诊断,可能会减轻我们农村人口中对癌症是一种致命疾病的负面认知。