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Clearing lactate is clearly better…but how much?*.清除乳酸显然更好……但具体好多少呢？*
Crit Care Med. 2014 Sep;42(9):2149-50. doi: 10.1097/CCM.0000000000000455.
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The riddle of hyperlactatemia.高乳酸血症之谜。
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The author replies.
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Don't take vitals, take a lactate.别测生命体征了，测个乳酸值。
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Lactate clearance as a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review study protocol.乳酸清除率作为预测危重症患者全因死亡率的有用生物标志物：一项系统评价研究方案
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The effect of low central venous pressure on hepatic surgical field bleeding and serum lactate in patients undergoing partial hepatectomy: a prospective randomized controlled trial.低中心静脉压对肝部分切除术患者肝手术野出血及血清乳酸的影响：一项前瞻性随机对照试验
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本文引用的文献

1
Lactate clearance is a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review and meta-analysis*.乳酸清除率是预测危重症患者全因死亡率的有用生物标志物：一项系统评价和荟萃分析*
Crit Care Med. 2014 Sep;42(9):2118-25. doi: 10.1097/CCM.0000000000000405.
2
Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock.严重脓毒症和感染性休克患者行定量复苏后全血乳酸动力学。
Chest. 2013 Jun;143(6):1548-1553. doi: 10.1378/chest.12-0878.
3
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.早期乳酸导向治疗 ICU 患者：一项多中心、开放标签、随机对照试验。
Am J Respir Crit Care Med. 2010 Sep 15;182(6):752-61. doi: 10.1164/rccm.200912-1918OC. Epub 2010 May 12.
4
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.乳酸清除率与中心静脉血氧饱和度作为早期脓毒症治疗目标的比较：一项随机临床试验。
JAMA. 2010 Feb 24;303(8):739-46. doi: 10.1001/jama.2010.158.

Clearing lactate is clearly better…but how much?*.

作者信息

Puskarich Michael A, Jones Alan E

机构信息

Department of Emergency Medicine, University of Mississippi Medical Center, Jackson, MS.

出版信息

Crit Care Med. 2014 Sep;42(9):2149-50. doi: 10.1097/CCM.0000000000000455.

DOI:10.1097/CCM.0000000000000455
PMID:25126809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4596229/
Abstract
摘要