妇科肿瘤研究组（GCIG）关于卵巢鳞状细胞癌的共识综述。
Gynecologic Cancer InterGroup (GCIG) consensus review for squamous cell carcinoma of the ovary.
作者信息
Glasspool Rosalind M, González Martín Antonio, Millan David, Lorusso Domenica, Åvall-Lundqvist Elisabeth, Hurteau Jean A, Davis Alison, Hilpert Felix, Kim Jae-Weon, Alexandre Jérôme, Ledermann Jonathan A
机构信息
*Beatson West of Scotland Cancer Centre, Glasgow, UK (SGCTG); †Medical Oncology Department, MD Anderson Cancer Centre, Madrid, Spain (GEICO); ‡Southern General Hospital, Glasgow, UK (SGCTG); §Gynecologic Oncology Unit, Fondazione IRCCS National Cancer institute of Milan (MITO), Milan, Italy; ‖Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden (NSGO); ¶Division of Gynecologic Oncology, NorthShore University Health System, University of Chicago Pritzker School of Medicine, Evanston, IL (GOG); #The Canberra Hospital, Canberra, Australia (ANZGOG); **University Hospital of Schleswig-Holstein Campus, Kiel, Germany (AGO); ††Department of Obstectrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea (KGOG); ‡‡Medical Oncology, Cochin-Hôtel Dieu, Paris Descartes University, Paris, France (GINECO); and §§UCL Cancer Institute, London, UK (NCRI/MRC).
出版信息
Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S26-9. doi: 10.1097/IGC.0000000000000209.
Squamous cell carcinoma of the ovary is a rare complication of mature cystic teratoma. The epidemiology, pathology, diagnosis, and management of this rare tumor are reviewed. Clinical characteristics, preoperative imaging, and tumor markers may help to predict malignancy preoperatively. Complete cytoreduction should be the aim of surgery. The prognosis for stage 1A disease is good, but for women with advanced or recurrent disease, it is very poor and has not improved in recent years. At present, there are insufficient data to provide clear guidance on the optimal management strategy for advanced disease, and there is a need to gain an understanding of the biology and to develop novel effective therapies. This will require coordinated international collaboration.
卵巢鳞状细胞癌是成熟囊性畸胎瘤的一种罕见并发症。本文对这种罕见肿瘤的流行病学、病理学、诊断及治疗进行了综述。临床特征、术前影像学检查及肿瘤标志物有助于术前预测恶性肿瘤。手术的目标应是完全细胞减灭术。1A期疾病的预后良好，但对于晚期或复发性疾病的女性，预后非常差且近年来并无改善。目前，尚无足够数据为晚期疾病的最佳治疗策略提供明确指导，有必要了解其生物学特性并开发新的有效治疗方法。这需要国际间的协作。
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