Indulkar Shreeya Taresh, Khare Manisha S, Shah Vinaya B, Khade Archana L
Department of Pathology, HBT Medical College and Dr. R. N. Cooper Hospital, Mumbai, Maharashtra, India.
J Midlife Health. 2018 Jan-Mar;9(1):44-46. doi: 10.4103/jmh.JMH_81_17.
Pure squamous cell carcinoma (SCC) of the ovary is rare. SCC can arise in a mature teratoma (MT), ovarian endometriosis or in a Brenner tumor. SCC is the most common malignant transformation arising in MT and comprises 80% of all cases. Such neoplastic transformations are extremely difficult either to predict or detect early. The mechanism of malignant transformation has not been completely understood. Due to the rarity and the aggressive course, diagnosis and treatment constitute a big challenge. We report a case of SCC arising in MT presenting with a huge abdominopelvic mass and abundant peritoneal collections clinically masquerading as abdominal tuberculosis. A review of literature with special emphasis on prognosis and treatment modalities is also presented.
卵巢纯鳞状细胞癌(SCC)较为罕见。SCC可发生于成熟畸胎瘤(MT)、卵巢子宫内膜异位症或勃勒纳瘤。SCC是MT中最常见的恶性转化类型,占所有病例的80%。这种肿瘤转化极难早期预测或检测。恶性转化的机制尚未完全明了。由于其罕见性及侵袭性病程,诊断和治疗构成了巨大挑战。我们报告1例发生于MT的SCC病例,临床表现为巨大的腹盆腔肿块及大量腹腔积液,临床上易误诊为腹部结核。本文还对文献进行了综述,特别强调了预后及治疗方式。