Koloszár S, Bártfai G, Godó G, Sas M
Department of Obstetrics and Gynaecology, Szent-Györgyi Albert University Medical School, Szeged, Hungary.
Acta Chir Hung. 1989;30(3):237-42.
Ovulation induction was performed by the pulsatile administration of subcutaneous human menopausal gonadotropin (hMG). Treatment was started with a daily dose of 75 IU hMG (in a 90% distribution), then it was increased to 150 IU depending on the oestradiol level of the plasma and on the result of folliculometry. Of 10 cycles treated ovulation was induced in 7 cases and two pregnancies occurred. In two cases, following a previous unsuccessful intramuscular hMG treatment, ovulation was induced. Hyperstimulation did not occur. The pulsatile s.c. administration of hMG seems to be an adequate ovulation-induction method in ovulatory disorders of hypothalamo-hypophyseal origin and is a good substitute for the missing, endogenous gonadotropin secretion of inadequate pace.
通过皮下注射人绝经期促性腺激素（hMG）脉冲给药进行促排卵。治疗开始时每日剂量为75IU hMG（90%的分布情况），然后根据血浆雌二醇水平和卵泡监测结果将剂量增加至150IU。在接受治疗的10个周期中，7例诱导排卵成功，2例怀孕。有2例之前肌肉注射hMG治疗失败，此次诱导排卵成功。未发生卵巢过度刺激综合征。皮下脉冲注射hMG似乎是下丘脑 - 垂体性排卵障碍的一种合适的促排卵方法，是内源性促性腺激素分泌不足时缺失部分的良好替代方法。
