Chang K H, Han M H, Choi Y W, Kim I O, Han M C, Kim C W
Department of Radiology, College of Medicine, Seoul National University, Korea.
AJNR Am J Neuroradiol. 1989 Nov-Dec;10(6):1255-62.
Tuberculosis (TB) is a rare cause of spinal arachnoiditis. It may occur primarily or secondary to intracranial or vertebral infection; unlike other types of arachnoiditis, it frequently involves the spinal cord as well as the meninges and the nerve roots. We retrospectively reviewed 13 conventional myelograms, eight CT myelograms, and five Gd-DTPA-enhanced MR images in 13 patients with spinal TB radiculomyelitis (arachnoiditis). Eleven patients had intracranial TB meningitis at the time of diagnosis or before. Ten patients were less than 30 years old. Conventional myelographic findings included a block of the CSF (11/13), most commonly at the level of the conus medullaris; irregular or indistinct thecal sac contour (9/13); multiple fine and/or coarse nodular defects (8/13); nerve-root thickening (7/13); and vertical bandlike adhesive defects (4/13). CT myelography showed intradural nodular masses suggesting tuberculomas at or just above the level of the block (4/8), irregularity of the spinal cord surface (4/8), irregular filling or obliteration of subarachnoidal space (6/8), and root thickening (5/8). Gd-DTPA-enhanced MR images revealed enhancing nodules suggesting tuberculomas (2/5); enhancement of the dura-arachnoid complex around the cord (3/5); and segmental enhancement of the thoracic cord, suggesting either infarction caused by vasculitis or TB myelitis in association with diffuse cord swelling (1/5). Plain MR findings were much less conspicuous, showing only an indistinct or irregular dura-arachnoid-cord complex (4/5). In conclusion, the conventional myelographic findings are considered to be virtually diagnostic of spinal TB radiculomyelitis in young patients with antecedent or coexisting TB meningitis.(ABSTRACT TRUNCATED AT 250 WORDS)
结核病(TB)是脊髓蛛网膜炎的罕见病因。它可原发性发生,或继发于颅内或椎体感染;与其他类型的蛛网膜炎不同,它常累及脊髓以及脑膜和神经根。我们回顾性分析了13例脊髓结核性脊神经根脊髓炎(蛛网膜炎)患者的13份传统脊髓造影、8份CT脊髓造影和5份钆-二乙三胺五乙酸(Gd-DTPA)增强磁共振成像。11例患者在诊断时或诊断前患有颅内结核性脑膜炎。10例患者年龄小于30岁。传统脊髓造影表现包括脑脊液梗阻(11/13),最常见于脊髓圆锥水平;鞘膜囊轮廓不规则或不清晰(9/13);多个细小和/或粗大的结节状缺损(8/13);神经根增粗(7/13);以及垂直带状粘连性缺损(4/13)。CT脊髓造影显示硬膜内结节状肿块,提示在梗阻水平或其上方有结核瘤(4/8),脊髓表面不规则(4/8),蛛网膜下腔不规则充盈或闭塞(6/8),以及神经根增粗(5/8)。Gd-DTPA增强磁共振成像显示提示结核瘤的强化结节(2/5);脊髓周围硬脑膜-蛛网膜复合体强化(3/5);胸段脊髓节段性强化,提示血管炎所致梗死或与弥漫性脊髓肿胀相关的结核性脊髓炎(1/5)。普通磁共振表现则不那么明显,仅显示不清晰或不规则的硬脑膜-蛛网膜-脊髓复合体(4/5)。总之,传统脊髓造影表现被认为对患有先前或并存结核性脑膜炎的年轻患者的脊髓结核性脊神经根脊髓炎具有几乎确诊的价值。(摘要截取自250字)