Germain P, Baruthio J, Roul G, Mossard J M, Bareiss P, Wecker D, Chambron J, Sacrez A
Service de cardiologie, hôpital de Hautepierre, Strasbourg.
Arch Mal Coeur Vaiss. 1989 Oct;82(10):1659-68.
Thirty-three patients presenting with regurgitation of the mitral valve (19 cases), tricuspid valve (14 cases) or aortic valve (11 cases) documented by angiography (n = 20) and/or doppler-echocardiography (n = 28) were examined by cine-MRI in order to test this method in valvular regurgitation. Sixteen ECG-synchronized cine-MRI images were acquired by the GRASS technique every 40 ms on appropriate projections, with a resistive 0.28 Tesla Bruker magnet. The semiology of normal and pathological blood flow images at cine-MRI is described. Valvular regurgitations present as "signal void" jets the chronology and spatial extension of which depend on the severity of the lesion. The differential diagnosis with physiological flows is discussed. The diagnostic sensitivity of the method was 29/29 when compared with angiography and 29/33 when compared with doppler-echocardiography (2 cases of 1/4 mitral regurgitation and 2 cases 1/4 tricuspid regurgitation were not visible at cine-MRI). The specificity of this method, as can be judged from 104 patients explored, also seems to be satisfactory. The severity of regurgitation was graded from 1 to 4 with the three methods, on the basis of strict criteria. The differences in grade evaluation exceeded +/- 1 point in only one case of mitral regurgitation which was greatly underestimated by the doppler method as compared with angiography and cine-MRI. Thus, cine-MRI is a reliable method to evaluate valvular regurgitations and their severity. It solves the practical problem raised by non-echogenic patients when catheterization is to be postponed or avoided.
对33例经血管造影(n = 20)和/或多普勒超声心动图(n = 28)证实存在二尖瓣反流(19例)、三尖瓣反流(14例)或主动脉瓣反流(11例)的患者进行电影磁共振成像(cine - MRI)检查,以测试该方法在瓣膜反流中的应用。使用0.28特斯拉的电阻式布鲁克磁体,通过GRASS技术每隔40毫秒在合适的投影上采集16幅心电图同步电影磁共振成像图像。描述了电影磁共振成像中正常和病理性血流图像的影像学特征。瓣膜反流表现为“信号缺失”喷射,其时间顺序和空间范围取决于病变的严重程度。讨论了与生理性血流的鉴别诊断。与血管造影相比,该方法的诊断敏感性为29/29,与多普勒超声心动图相比为29/33(电影磁共振成像未显示4例二尖瓣反流中的2例和4例三尖瓣反流中的2例)。从104例接受检查的患者判断,该方法的特异性似乎也令人满意。根据严格标准,用这三种方法将反流严重程度分为1至4级。在仅1例二尖瓣反流中,与血管造影和电影磁共振成像相比,多普勒方法对反流严重程度的分级评估差异超过±1分,该病例被多普勒方法严重低估。因此,电影磁共振成像是评估瓣膜反流及其严重程度的可靠方法。它解决了在推迟或避免导管插入术时非超声心动图检查患者所带来的实际问题。