Zhimulev I F, Beliaeva E S, Mal'tseva N I, Bol'shakov V N
Genetika. 1989 Sep;25(9):1589-98.
Compaction of chromosome regions translocated to the pericentric heterochromatin and the break frequency in intercalary heterochromatin (IH) regions as affected by position effect modifiers (low temperature, removing the Y chromosome, genetic enhancers and suppressors) were studied. It has been shown that the factors enhancing compaction also increase the break frequency in IH regions. Data obtained are discussed from the point of view of proteins affecting the compaction of intercalary and pericentric heterochromatin regions translocated to heterochromatin under position effect.
研究了易位到着丝粒周围异染色质的染色体区域的压缩以及居间异染色质(IH)区域中的断裂频率,这些受位置效应修饰因子(低温、去除Y染色体、遗传增强子和抑制子)的影响。结果表明,增强压缩的因素也会增加IH区域中的断裂频率。从蛋白质影响在位置效应下易位到异染色质的居间和着丝粒周围异染色质区域压缩的角度对所获得的数据进行了讨论。