通过 N-磺酰基-1,2,3-三唑对末端炔烃和叠氮化物的薁进行非对映选择性 N-磺酰基氨基烯丙基化反应。

Diastereoselective N-sulfonylaminoalkenylation of azulenes from terminal alkynes and azides via N-sulfonyl-1,2,3-triazoles.

机构信息

Department of Chemistry, Kangwon National University , Chuncheon 200-701, Republic of Korea.

出版信息

Org Lett. 2014 Sep 5;16(17):4468-71. doi: 10.1021/ol502208w. Epub 2014 Aug 18.

Abstract

The development of rhodium-catalyzed diastereoselective N-sulfonylaminoalkenylation of azulenes using N-sulfonyltriazoles is described. This procedure can be successfully applied to rhodium-catalyzed diastereoselective N-sulfonylaminoalkenylation of azulenes starting from terminal alkynes and N-sulfonylazides via a three-component semi-one-pot process.

摘要

本文描述了使用 N-磺酰基三唑发展的螺[环戊烯-2,1'-吲哚]的铑催化非对映选择性 N-磺酰基氨基烯化反应。该方法可以通过三组分半一锅法，成功应用于从末端炔烃和 N-磺酰基叠氮化物出发的螺[环戊烯-2,1'-吲哚]的铑催化非对映选择性 N-磺酰基氨基烯化反应。