左归丸治疗妊娠期糖尿病大鼠的疗效。

The therapeutic effect of zuogui wan in gestational diabetes mellitus rats.

机构信息

Beijing University of Chinese Medicine, No. 11 North Third Ring Road, Chaoyang District, Beijing 100029, China.

Shanxi University of Traditional Chinese Medicine, No. 89 Jinci road, Taiyuan, Shanxi 030024, China.

出版信息

J Anal Methods Chem. 2014;2014:737961. doi: 10.1155/2014/737961. Epub 2014 Jul 22.

DOI:10.1155/2014/737961

PMID:25136475

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4129929/

Abstract

In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitus rats as the control group (group II, n = 11), and (3) rats of normal pregnancy group (group III, n = 11). Compared with gestational diabetes mellitus rats as the control group, Zuogui Wan can change the indexes of fasting blood glucose, body weight, total cholesterol, insulin, and metabolism cage index significantly in Zuogui Wan gestational diabetes mellitus group. We can conclude that Zuogui Wan has the therapeutic effect on gestational diabetes mellitus.

摘要

在这项实验中，我们使用链脲佐菌素建立了妊娠期糖尿病大鼠动物模型。使用 GDM 大鼠模型，将 1-19 天的孕鼠分为三组：（1）左归丸妊娠期糖尿病组（I 组，n = 12），（2）妊娠期糖尿病大鼠对照组（II 组，n = 11），和（3）正常妊娠大鼠组（III 组，n = 11）。与妊娠期糖尿病大鼠对照组相比，左归丸可明显改变左归丸妊娠期糖尿病组的空腹血糖、体重、总胆固醇、胰岛素和代谢笼指数等指标。我们可以得出结论，左归丸对妊娠期糖尿病有治疗作用。