Hochstrate P
Institut für Tierphysiologie, Ruhr-Universität Bochum, Federal Republic of Germany.
J Comp Physiol A. 1989 Dec;166(2):179-87. doi: 10.1007/BF00193462.
The effect of lanthanum on the light response of blowfly (Calliphora erythrocephala) photoreceptors was studied. The electrophysiological behaviour of the photoreceptors in the presence of La can be summarized as follows: 1. Upon long stimulation the photoreceptors responded with a 'transient receptor potential', i.e. the cells depolarized at the onset of the stimulus and then repolarized to (or below) the resting potential. This effect was dependent on stimulus intensity and occurred only at high intensities. During illumination membrane noise was reduced. 2. The light-induced changes in membrane potential were paralleled by changes in membrane resistance. 3. The time course of the receptor response was slowed down. 4. Light adaptation led to an increase in response latency. 5. The recovery of the receptor response after light adaptation was slowed down. 6. The sensitivity of the receptor cells measured by the response to short light stimuli was reduced. In summary, the electrophysiological behaviour of Calliphora photoreceptors in the presence of La was very similar to that of the photoreceptors of the trp (transient receptor potential) mutant of Drosophila melanogaster. This result suggests that La and trp mutation affect the same cellular processes in the photoreceptors.
研究了镧对红头丽蝇（Calliphora erythrocephala）光感受器光反应的影响。在镧存在的情况下，光感受器的电生理行为可总结如下：1. 长时间刺激时，光感受器会产生“瞬时感受器电位”，即细胞在刺激开始时去极化，然后再复极化至（或低于）静息电位。这种效应取决于刺激强度，且仅在高强度时出现。光照期间膜噪声降低。2. 膜电位的光诱导变化与膜电阻的变化平行。3. 感受器反应的时间进程减慢。4. 光适应导致反应潜伏期延长。5. 光适应后感受器反应的恢复减慢。6. 通过对短光刺激的反应测量，感受器细胞的敏感性降低。总之，在镧存在的情况下，红头丽蝇光感受器的电生理行为与黑腹果蝇trp（瞬时感受器电位）突变体的光感受器非常相似。这一结果表明，镧和trp突变影响光感受器中的相同细胞过程。
