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脑部环形强化病变:诊断难题。

Ring-enhancing lesions in the brain: a diagnostic dilemma.

作者信息

Shetty Guruprasada, Avabratha Kadke Shreedhara, Rai Boodyar Sanjeev

机构信息

Department of Pediatrics, Father Muller Medical College, MangaloreKarnataka, India.

出版信息

Iran J Child Neurol. 2014 Summer;8(3):61-4.

Abstract

The most common radiological abnormality seen in young Indian patients with epilepsy is single small enhancing (ring/disc) computed tomographic (CT) lesions. The two most common differential diagnosis of this lesion in clinical practice include neurocysticercosis (NCC) and tuberculomas. They have similar clinical and neuroimaging features. Few researchers believe that in poor and developing countries (where both tuberculosis and NCC are common) that it is difficult to differentiate between tuberculomas and a single cysticercal granulomas. We report a case of a 6-year-old female patient who presented with complex partial seizures. The patient's neuroimaging showed a single ring-enhancing lesion in the brain that was not differentiated between NCC and Tuberculoma. Finally, Magnetic resonance spectroscopy (MRS) was suggestive of tuberculoma that was successfully treated with antituberculosis therapy. This report highlights diagnostic difficulties with conventional investigations in single ring enhancing lesions in the brain and role of MRS in a diagnosis.MRS is helpful in differentiating these two conditions.

摘要

在患有癫痫的年轻印度患者中,最常见的放射学异常是单个小的强化(环形/盘状)计算机断层扫描(CT)病变。在临床实践中,这种病变最常见的两种鉴别诊断包括神经囊尾蚴病(NCC)和结核瘤。它们具有相似的临床和神经影像学特征。很少有研究人员认为,在贫穷和发展中国家(结核病和NCC都很常见),很难区分结核瘤和单个囊尾蚴肉芽肿。我们报告一例6岁女性患者,表现为复杂部分性发作。患者的神经影像学显示脑部有一个单个环形强化病变,无法区分是NCC还是结核瘤。最后,磁共振波谱(MRS)提示为结核瘤,经抗结核治疗成功治愈。本报告强调了脑部单个环形强化病变常规检查的诊断困难以及MRS在诊断中的作用。MRS有助于区分这两种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577a/4135283/e2981a2d70d3/ijcn-8-061-g001.jpg

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