Sethi P P, Wadia R S, Kiyawat D P, Ichaporia N R, Kothari S S, Sangle S A, Wadhwa P
Department of Neurology, Ruby Hall Clinic, Pune, India.
J Trop Med Hyg. 1994 Dec;97(6):347-53.
In India a common CT finding in epilepsy is a ring/disc enhancing lesion (RDEL). This lesion is hypodense on plain scan and shows a ring or disc-like enhancement on contrast CT scan. This study reports on 186 cases with such lesions, found in 26.1% of all focal epilepsy. It was commoner in children. Fifty-three per cent of the cases had had fits for less than 3 months, 29.6% had had fits for more than 6 months and 17.6% for more than a year. Focal signs were seen in 20% of cases and focal EEG slowing in 57.1%. The lesion cleared on anticonvulsants alone in 75% of cases. At present this is the preferred method of treatment unless there is coexisting CNS tuberculosis or close family contact with TB or extraneural cysticercosis. Biopsy was done in 16 cases and the two commonest causes were found to be cysticercosis and tuberculosis. A review of 58 biopsies in four centres in India is included. The frequency of this entity is apparently highest in India and even in other countries where cysticercosis is common, the lesion is not reported as frequently.
在印度，癫痫患者常见的CT表现是环形/盘状强化病灶（RDEL）。该病灶在平扫时呈低密度，在增强CT扫描时呈环形或盘状强化。本研究报告了186例有此类病灶的病例，占所有局灶性癫痫患者的26.1%。在儿童中更为常见。53%的病例发作时间不到3个月，29.6%的病例发作时间超过6个月，17.6%的病例发作时间超过1年。20%的病例有局灶性体征，57.1%的病例脑电图有局灶性减慢。75%的病例仅通过抗惊厥药物治疗后病灶消失。目前，除非同时存在中枢神经系统结核或与结核病患者密切家庭接触或存在神经外囊尾蚴病，否则这是首选的治疗方法。对16例患者进行了活检，发现最常见的两种病因是囊尾蚴病和结核病。本文还纳入了对印度四个中心58例活检病例的回顾。该病变在印度的发生率显然最高，即使在囊尾蚴病常见的其他国家，这种病变的报告也没有这么频繁。
