Wolf G, Müller G M, Kehrberg G
Radiobiol Radiother (Berl). 1989;30(6):546-52.
From numerous investigations it is known that lithium carbonate promotes granulocytopoiesis by stimulation of CSF (colony stimulating factor) in bone marrow. To prove if no immature, in their functions restricted cells are delivered from bone marrow, the activity of granulocytes was tested in vitro in patients with lithium therapy. It could be seen that granulocytes of peripheral blood show an increased in-vitro-activation after lithium influence in vivo.
从大量研究中可知,碳酸锂通过刺激骨髓中的集落刺激因子(CSF)促进粒细胞生成。为了证明骨髓中是否没有功能受限的未成熟细胞被释放出来,对接受锂治疗的患者的粒细胞活性进行了体外测试。可以看出,外周血粒细胞在体内受到锂影响后,其体外活性有所增加。