Guo Xiaohua, Zhang Yu, Xu Guojun, Zhou Xianhui, Li Lei, Tang Baopeng
Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China. Email:
Zhonghua Nei Ke Za Zhi. 2014 May;53(5):371-4.
To investigate the clinical features and current therapy of atrial fibrillation (AF) of inpatients in Urumqi, China.
The clinical data of inpatients diagnosed with AF from January, 2008 to December, 2012, in 12 hospitals in Urumqi were retrospectively analyzed.
Totally 1 310 AF inpatients were enrolled in this study with the age of (64.8 ± 3.3) years old and a men to women ratio of 1.39. Most patients were in age groups of 61-70 years (26.5%) and 71-80 years (27.6%). More patients with paroxysmal AF were at cardiac function class I-II (75.2%), while more patients with persistent AF were at cardiac function class III-IV (31.0%) (both P values < 0.05). The most common co-morbidities of AF were hypertension (49.2%), coronary heart disease (38.5%), diabetes mellitus (20.1%). Compared with patients of chronic AF, the patients of paroxysmal AF had higher success rates in amiodarone conversation and sinus rhythm maintenance after ablation (44.8% vs 29.9%, 87.5% vs 68.9%, P values < 0.05). Among the 1 310 inpatients, 992 patients (75.7%) received antithrombotic therapy. There were statistically significant differences in CHA2DS2 score and incidence rate of cerebral infarction among patients receiving aspirin, warfarin or rivaroxaban/other anticoagulation drugs [2(1, 3) vs 3(2, 4) vs 3(2, 5) and 6.3% vs 23.8% vs 30.2%, both P values < 0.05].
Our results of AF inpatients' age, gender, related disease distribution, AF types, incidence of stoke, therapeutic and epidemiological features are in accordance with the domestic and abroad reports.
探讨中国乌鲁木齐住院心房颤动（房颤）患者的临床特征及当前治疗情况。
回顾性分析2008年1月至2012年12月乌鲁木齐12家医院诊断为房颤的住院患者的临床资料。
本研究共纳入1310例房颤住院患者，年龄为（64.8±3.3）岁，男女比例为1.39。大多数患者年龄在61 - 70岁组（26.5%）和71 - 80岁组（27.6%）。阵发性房颤患者心功能Ⅰ - Ⅱ级者较多（75.2%），而持续性房颤患者心功能Ⅲ - Ⅳ级者较多（31.0%）（P值均<0.05）。房颤最常见的合并症为高血压（49.2%）、冠心病（38.5%）、糖尿病（20.1%）。与慢性房颤患者相比，阵发性房颤患者在胺碘酮转复及消融术后窦性心律维持方面成功率更高（44.8%对29.9%，87.5%对68.9%，P值<0.05）。在1310例住院患者中，992例（75.7%）接受了抗栓治疗。接受阿司匹林、华法林或利伐沙班/其他抗凝药物治疗的患者在CHA2DS2评分及脑梗死发生率方面存在统计学显著差异[2（1，3）对3（2，4）对3（2，5）以及6.3%对23.8%对30.2%，P值均<0.05]。
我们关于房颤住院患者的年龄、性别、相关疾病分布、房颤类型、卒中发生率、治疗及流行病学特征的结果与国内外报道一致。
