Estrade G, Garnier D, Bernasconi F, Donatien Y
Service de cardiologie, CHR La Meynard, Fort-de-France.
Arch Mal Coeur Vaiss. 1989 Nov;82(11):1903-5.
The authors report the case of a Bothrops lanceolatus snake bite complicated by severe pulmonary embolism a few hours after admission. This thromboembolic complication developed despite heparin therapy and was followed by disseminated intravascular coagulation (DIC). Vascular thrombosis and pulmonary embolism are rare after Bothrops lanceolatus snake bite as patients are usually hypocoagulable due to DIC. In this case, the thromboembolism was probably caused by the procoagulant effect of the thrombin-like enzymes of the snake venom which may have been injected directly into the vein of a young woman taking a contraceptive pill. A specific antivenin which has recently become available fort treatment may decrease the complications of Bothrops lanceolatus snake bite.
作者报告了一例矛头蝮蛇咬伤病例,患者在入院数小时后并发严重肺栓塞。尽管进行了肝素治疗,但仍出现了这种血栓栓塞并发症,随后发展为弥散性血管内凝血(DIC)。矛头蝮蛇咬伤后血管血栓形成和肺栓塞很少见,因为患者通常因DIC而处于低凝状态。在该病例中,血栓栓塞可能是由蛇毒中类凝血酶的促凝血作用引起的,这些酶可能直接注入了一名正在服用避孕药的年轻女性的静脉中。最近可用的一种特效抗蛇毒血清可能会减少矛头蝮蛇咬伤的并发症。