Hessling Gabriele
Abteilung Elektrophysiologie, Deutsches Herzzentrum München, Lazarettstr. 36, 80636, München, Deutschland,
Herzschrittmacherther Elektrophysiol. 2014 Sep;25(3):166-71. doi: 10.1007/s00399-014-0337-3. Epub 2014 Aug 23.
Over the past decades, interventional therapy of tachyarrhythmias in children without structural heart disease has evolved as an alternative to chronic pharmacological treatment. Catheter ablation in children over 5 years with symptomatic tachycardia using radiofrequency- or cryoenergy is nowadays performed with high success and low complication rates at experienced centers. The use of modern technologies such as non-fluoroscopic 3-dimensional mapping has further increased efficacy and safety of catheter ablation, and has led to a significant reduction of fluoroscopy time and dose.Arrhythmia substrates treated most frequently by catheter ablation in children include accessory pathways (WPW syndrome) leading to atrioventricular reentrant tachycardia (AVRT) and dual AV nodal pathways causing atrioventricular nodal reentrant tachycardia (AVNRT). Success rates of catheter ablation for these substrates during long-term follow up are over 90 %. Less common forms of tachycardias in children, such as focal atrial tachycardia, ventricular outflow tachycardias or idiopathic left ventricular tachycardia, are also amenable to catheter ablation with good long-term results. In asymptomatic children with preexcitation on the surface ECG (accessory pathway with the risk of rapid antegrade conduction during atrial fibrillation) the indication for catheter ablation of the accessory pathway for the prevention of sudden cardiac death should already be evaluated during childhood.
在过去几十年中,无结构性心脏病儿童快速心律失常的介入治疗已发展成为慢性药物治疗的替代方法。如今,在经验丰富的中心,对5岁以上有症状性心动过速的儿童使用射频或冷冻能量进行导管消融,成功率高且并发症发生率低。使用非透视三维标测等现代技术进一步提高了导管消融的有效性和安全性,并显著减少了透视时间和剂量。儿童导管消融最常治疗的心律失常基质包括导致房室折返性心动过速(AVRT)的旁路(WPW综合征)和引起房室结折返性心动过速(AVNRT)的双房室结通路。这些基质在长期随访期间的导管消融成功率超过90%。儿童较少见的心动过速形式,如局灶性房性心动过速、室性流出道心动过速或特发性左心室心动过速,也适合进行导管消融,长期效果良好。对于体表心电图有预激的无症状儿童(存在房颤时快速前向传导风险的旁路),在儿童期就应评估导管消融旁路以预防心脏性猝死的指征。