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使用新型机器人引导进行图像引导微波热消融治疗肝肿瘤:初步经验。

Image-guided microwave thermoablation of hepatic tumours using novel robotic guidance: an early experience.

机构信息

Institute for Diagnostic and Interventional Radiology, Klinikum Bad Salzungen, Lindigalle 3, 36433, Bad Salzungen, Germany,

出版信息

Eur Radiol. 2015 Feb;25(2):454-62. doi: 10.1007/s00330-014-3398-0. Epub 2014 Aug 23.

Abstract

OBJECTIVE

To evaluate and compare novel robotic guidance and manual approaches based on procedural accuracy, procedural time, procedural performance, image quality as well as patient dose during image-guided microwave thermoablation.

METHOD

The study was prospectively performed between June 2013 and December 2013 using 70 patients. Forty randomly selected patients (group 1) were treated with manual guidance and 30 patients (group 2) were treated using a novel robotic guidance. Parameters evaluated were procedural accuracy, total procedural time, procedural performance, quantitative/qualitative image quality and patient dose. Two-sided Student's t test and Wilcoxon rank-sum test were used to test the significance of the data and p values less than 0.05 were considered statistically significant.

RESULT

Accuracy parameters were significantly higher in group 2 (all p < 0.05). Total procedural time showed a mean time difference of 3 min (group 2 > group 1; p = 0.0008). Volume CT dose index and dose-length product were significantly lower for group 2 compared to group 1 (all p < 0.05) for CT fluoroscopy imaging. Total procedural performance score was higher for group 2 compared to group 1 (p = 0.0001). Image quality parameters were insignificant between examined groups.

CONCLUSION

The novel robotic guided approach improved the accuracy of targeting the target tumour, reduced patient dose and increased procedural performance (which influences the procedural safety) during ablation.

KEY POINTS

• Few reports are available in the literature regarding robotic-assisted liver microwave ablation. • The robotic guided approach improved accuracy of localizing the target tumour. • Radiation dose on patients was reduced with the robotic guidance. • Numbers of insertions and readjustments were reduced, lowering chances of complications.

摘要

目的

评估并比较基于程序准确性、程序时间、程序性能、图像质量以及图像引导微波热消融过程中患者剂量的新型机器人引导和手动方法。

方法

本研究于 2013 年 6 月至 2013 年 12 月期间前瞻性地进行,共纳入 70 例患者。40 例随机选择的患者(第 1 组)接受手动引导治疗,30 例患者(第 2 组)接受新型机器人引导治疗。评估的参数包括程序准确性、总程序时间、程序性能、定量/定性图像质量和患者剂量。采用双侧学生 t 检验和 Wilcoxon 秩和检验来检验数据的显著性,p 值小于 0.05 被认为具有统计学意义。

结果

第 2 组的准确性参数显著更高(均 p<0.05)。第 2 组的总程序时间比第 1 组平均长 3 分钟(p=0.0008)。与第 1 组相比,第 2 组的容积 CT 剂量指数和剂量长度乘积显著更低(均 p<0.05),这是在 CT 透视成像时的结果。第 2 组的总程序性能评分明显高于第 1 组(p=0.0001)。两组间的图像质量参数无显著差异。

结论

新型机器人引导方法提高了靶向目标肿瘤的准确性,降低了患者剂量,并提高了消融过程中的程序性能(这会影响程序安全性)。

关键点

  • 关于机器人辅助肝微波消融,文献中报道较少。

  • 机器人引导方法提高了定位目标肿瘤的准确性。

  • 患者的辐射剂量降低,这是机器人引导的结果。

  • 减少了插入和调整的次数,降低了并发症发生的几率。

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