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本文引用的文献

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Safety margin assessment after microwave ablation of liver tumors: inter- and intrareader variability.肝脏肿瘤微波消融治疗后安全性评估:组内和组间观察者变异性。
Radiol Oncol. 2020 Feb 12;54(1):57-61. doi: 10.2478/raon-2020-0004.
2
Robotic versus Freehand Needle Positioning in CT-guided Ablation of Liver Tumors: A Randomized Controlled Trial.机器人与徒手定位在 CT 引导下肝脏肿瘤消融中的对比:一项随机对照试验。
Radiology. 2019 Mar;290(3):826-832. doi: 10.1148/radiol.2018181698. Epub 2019 Jan 22.
3
1000 consecutive ablation sessions in the era of computer assisted image guidance - Lessons learned.计算机辅助图像引导时代的1000次连续消融治疗——经验教训
Eur J Radiol Open. 2018 Dec 5;6:1-8. doi: 10.1016/j.ejro.2018.11.002. eCollection 2019.
4
Robotic Insertion of Various Ablation Needles Under Computed Tomography Guidance: Accuracy in Animal Experiments.在计算机断层扫描引导下机器人插入各种消融针:动物实验中的准确性。
Eur J Radiol. 2018 Aug;105:162-167. doi: 10.1016/j.ejrad.2018.06.006. Epub 2018 Jun 12.
5
Microwave Ablation in the Management of Colorectal Cancer Pulmonary Metastases.微波消融治疗结直肠癌肺转移
Cardiovasc Intervent Radiol. 2018 Oct;41(10):1530-1544. doi: 10.1007/s00270-018-2000-6. Epub 2018 May 29.
6
Stereotactically navigated percutaneous microwave ablation (MWA) compared to conventional MWA: a matched pair analysis.立体定向导航经皮微波消融(MWA)与传统 MWA 的比较:配对分析。
Int J Comput Assist Radiol Surg. 2018 Dec;13(12):1991-1997. doi: 10.1007/s11548-018-1778-7. Epub 2018 May 4.
7
Radiofrequency ablation compared to surgical resection for curative treatment of patients with colorectal liver metastases - a meta-analysis.射频消融与手术切除治疗结直肠癌肝转移患者的疗效比较——一项荟萃分析
HPB (Oxford). 2017 Sep;19(9):749-756. doi: 10.1016/j.hpb.2017.05.011. Epub 2017 Jul 4.
8
Local Treatment of Unresectable Colorectal Liver Metastases: Results of a Randomized Phase II Trial.不可切除结直肠癌肝转移的局部治疗:一项随机II期试验的结果
J Natl Cancer Inst. 2017 Sep 1;109(9). doi: 10.1093/jnci/djx015.
9
Evaluation of a robotic system for irreversible electroporation (IRE) of malignant liver tumors: initial results.用于恶性肝肿瘤不可逆电穿孔(IRE)的机器人系统评估:初步结果。
Int J Comput Assist Radiol Surg. 2017 May;12(5):803-809. doi: 10.1007/s11548-016-1485-1. Epub 2016 Sep 21.
10
Evaluation of a Robotic Assistance-System For Percutaneous Computed Tomography-Guided (CT-Guided) Facet Joint Injection: A Phantom Study.用于经皮计算机断层扫描引导(CT引导)小关节突关节注射的机器人辅助系统的评估:一项体模研究。
Med Sci Monit. 2016 Sep 20;22:3334-9. doi: 10.12659/msm.900686.

利用机器人导航系统提高恶性肝肿瘤微波消融的主要疗效。

Improvement of the primary efficacy of microwave ablation of malignant liver tumors by using a robotic navigation system.

机构信息

Department of Radiology, University Medical Center Regensburg, Regensburg, Germany.

Center for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany.

出版信息

Radiol Oncol. 2020 May 28;54(3):295-300. doi: 10.2478/raon-2020-0033.

DOI:10.2478/raon-2020-0033
PMID:32463387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7409605/
Abstract

Background The aim of the study was to assess the primary efficacy of robot-assisted microwave ablation and compare it to manually guided microwave ablation for percutaneous ablation of liver malignancies. Patients and methods We performed a retrospective single center evaluation of microwave ablations of 368 liver tumors in 192 patients (36 female, 156 male, mean age 63 years). One hundred and nineteen ablations were performed between 08/2011 and 03/2014 with manual guidance, whereas 249 ablations were performed between 04/2014 and 11/2018 using robotic guidance. A 6-week follow-up (ultrasound, computed tomography and magnetic resonance imaging) was performed on all patients. Results The primary technique efficacy outcome of the group treated by robotic guidance was significantly higher than that of the manually guided group (88% vs. 76%; p = 0.013). Multiple logistic regression analysis indicated that a small tumor size (≤ 3 cm) and robotic guidance were significant favorable prognostic factors for complete ablation. Conclusions In addition to a small tumor size, robotic navigation was a major positive prognostic factor for primary technique efficacy.

摘要

背景

本研究旨在评估机器人辅助微波消融的主要疗效,并将其与手动引导微波消融治疗肝恶性肿瘤的疗效进行比较。

患者和方法

我们对 192 名患者的 368 个肝脏肿瘤进行了回顾性单中心评估(36 名女性,156 名男性,平均年龄 63 岁)。119 例在 2011 年 8 月至 2014 年 3 月期间采用手动引导进行消融,而 249 例在 2014 年 4 月至 2018 年 11 月期间采用机器人引导进行消融。所有患者均接受 6 周的随访(超声、计算机断层扫描和磁共振成像)。

结果

机器人引导组的主要技术疗效明显高于手动引导组(88%对 76%;p = 0.013)。多因素逻辑回归分析表明,肿瘤体积小(≤3cm)和机器人引导是完全消融的主要有利预后因素。

结论

除了肿瘤体积小外,机器人导航也是主要的技术疗效的正预后因素。