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利用机器人导航系统提高恶性肝肿瘤微波消融的主要疗效。

Improvement of the primary efficacy of microwave ablation of malignant liver tumors by using a robotic navigation system.

机构信息

Department of Radiology, University Medical Center Regensburg, Regensburg, Germany.

Center for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany.

出版信息

Radiol Oncol. 2020 May 28;54(3):295-300. doi: 10.2478/raon-2020-0033.

Abstract

Background The aim of the study was to assess the primary efficacy of robot-assisted microwave ablation and compare it to manually guided microwave ablation for percutaneous ablation of liver malignancies. Patients and methods We performed a retrospective single center evaluation of microwave ablations of 368 liver tumors in 192 patients (36 female, 156 male, mean age 63 years). One hundred and nineteen ablations were performed between 08/2011 and 03/2014 with manual guidance, whereas 249 ablations were performed between 04/2014 and 11/2018 using robotic guidance. A 6-week follow-up (ultrasound, computed tomography and magnetic resonance imaging) was performed on all patients. Results The primary technique efficacy outcome of the group treated by robotic guidance was significantly higher than that of the manually guided group (88% vs. 76%; p = 0.013). Multiple logistic regression analysis indicated that a small tumor size (≤ 3 cm) and robotic guidance were significant favorable prognostic factors for complete ablation. Conclusions In addition to a small tumor size, robotic navigation was a major positive prognostic factor for primary technique efficacy.

摘要

背景

本研究旨在评估机器人辅助微波消融的主要疗效,并将其与手动引导微波消融治疗肝恶性肿瘤的疗效进行比较。

患者和方法

我们对 192 名患者的 368 个肝脏肿瘤进行了回顾性单中心评估(36 名女性,156 名男性,平均年龄 63 岁)。119 例在 2011 年 8 月至 2014 年 3 月期间采用手动引导进行消融,而 249 例在 2014 年 4 月至 2018 年 11 月期间采用机器人引导进行消融。所有患者均接受 6 周的随访(超声、计算机断层扫描和磁共振成像)。

结果

机器人引导组的主要技术疗效明显高于手动引导组(88%对 76%;p = 0.013)。多因素逻辑回归分析表明,肿瘤体积小(≤3cm)和机器人引导是完全消融的主要有利预后因素。

结论

除了肿瘤体积小外,机器人导航也是主要的技术疗效的正预后因素。

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