阿替洛尔、美托洛尔、醋丁洛尔、普拉洛尔、普萘洛尔和吲哚洛尔对麻醉犬心脏和支气管β-肾上腺素能受体的拮抗作用强度
Cardiac and bronchial beta-adrenoceptor antagonistic potencies of atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol in the anaesthetized dog.
作者信息
Harms H H, Spoelstra A J
出版信息
Clin Exp Pharmacol Physiol. 1978 Jan-Feb;5(1):53-9. doi: 10.1111/j.1440-1681.1978.tb00651.x.
Abstract
- The beta-adrenoceptor antagonists atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol have been tested for their ability to reduce isoprenaline-induced bronchodilation and tachycardia in the anaesthetized dog. 2. Atenolol, metoprolol, acebutolol and practolol all possessed a similar degree of cardioselectivity in this animal model.
摘要
- 已对β肾上腺素能受体拮抗剂阿替洛尔、美托洛尔、醋丁洛尔、普拉洛尔、普萘洛尔和吲哚洛尔降低麻醉犬异丙肾上腺素诱导的支气管扩张和心动过速的能力进行了测试。2. 在该动物模型中，阿替洛尔、美托洛尔、醋丁洛尔和普拉洛尔均具有相似程度的心脏选择性。
Zotero 插件