Miyata Yohane, Shimazaki Makiko, Komatsu Yumiko, Nakamura Yukiko, Oka Akira
No To Hattatsu. 2014 Jul;46(4):301-6.
An 11-year-old boy, who had no remarkable past history, exhibited disorientation and abnormal behavior lasting for several hours. Continuous ictal discharges on his EEG lead to the diagnosis of nonconvulsive status epilepticus (NCSE). The administration of diazepam instantly resulted in the cessation of ictal discharges, associated with clinical recovery. Interictal spikes distributed in frontal lobes are sporadically seen, suggesting frontal lobe as an epileptic focus. After starting medication, he showed excellent clinical course without recurrence of seizure or neurological sequelae. Although NCSE is generally suggestive of poor prognosis, some subtypes of NCSE, such as partial status epilepticus and absence status epilepticus, are not always associated with adverse outcome. The present case suggests that epileptic patients who present NCSE at onset and lack interictal neurological impairments might have good outcome.
一名11岁男孩，既往史无特殊，出现定向障碍和异常行为持续数小时。脑电图显示持续性发作期放电，诊断为非惊厥性癫痫持续状态（NCSE）。给予地西泮后发作期放电立即停止，临床症状恢复。发作间期棘波偶见于额叶，提示额叶为癫痫病灶。开始用药后，他临床过程良好，无癫痫复发或神经后遗症。虽然NCSE通常提示预后不良，但NCSE的一些亚型，如部分性癫痫持续状态和失神性癫痫持续状态，并不总是与不良结局相关。本病例提示，起病时出现NCSE且无发作间期神经功能损害的癫痫患者可能预后良好。
