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会阴直肠乙状结肠切除术后复发:时间及原因?

Recurrence after perineal rectosigmoidectomy: when and why?

作者信息

Kim M, Reibetanz J, Schlegel N, Krajinovic K, Köstler H, Germer C-T, Isbert C

机构信息

Department of General, Gastrointestinal, Vascular and Paediatric Surgery, University Hospital Wuerzburg, Wuerzburg, Germany.

出版信息

Colorectal Dis. 2014 Nov;16(11):920-4. doi: 10.1111/codi.12756.

Abstract

AIM

Reported recurrence rates after perineal rectosigmoidectomy (Altemeier's procedure) in patients with full-thickness rectal prolapse vary from 0% to 60%. The object of this study was to analyse risk factors for recurrence after this procedure.

METHOD

From May 2004 to December 2012, 63 consecutive patients suffering from full-thickness rectal prolapse undergoing perineal rectosigmoidectomy were included. Of these 46 were female and the median age of the whole group was 79 (30-90) years. The median follow-up was 53 (3-99) months. Patient characteristics and operative parameters were compared between patients with and without recurrence.

RESULTS

One patient died and another patient needed re-operation. Eight full-thickness recurrences occurred in eight patients after a median of 18 (6-48) months. Stapled compared with handsewn anastomosis (hazard ratio 7.96, 95% confidence interval 1.90-33.47; P = 0.001) and shorter specimen length (hazard ratio 4.06, 95% confidence interval 0.97-16.99; P = 0.03) increased the risk of recurrence in Cox regression analysis.

CONCLUSION

The operative technique including stapled anastomosis and length of the resected specimen seems to be associated with a high recurrence rate after perineal rectosigmoidectomy.

摘要

目的

全层直肠脱垂患者行会阴直肠乙状结肠切除术(阿尔特迈尔手术)后的复发率报道为0%至60%。本研究的目的是分析该手术后复发的危险因素。

方法

纳入2004年5月至2012年12月期间连续63例行会阴直肠乙状结肠切除术的全层直肠脱垂患者。其中46例为女性,全组患者的年龄中位数为79岁(30 - 90岁)。中位随访时间为53个月(3 - 99个月)。比较复发患者和未复发患者的患者特征及手术参数。

结果

1例患者死亡,另1例患者需要再次手术。8例患者出现全层复发,中位复发时间为18个月(6 - 48个月)。在Cox回归分析中,与手工缝合吻合相比,吻合器吻合(风险比7.96,95%置信区间1.90 - 33.47;P = 0.001)以及标本长度较短(风险比4.06,95%置信区间0.97 - 16.99;P = 0.03)会增加复发风险。

结论

包括吻合器吻合和切除标本长度在内的手术技术似乎与会阴直肠乙状结肠切除术后的高复发率相关。

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