Manuilova I A, Sotnikova E I, Shchedrina R N, Torganova I G, Nazarenko T A, Zykin B I
Akush Ginekol (Mosk). 1989 Oct(10):14-8.
A comparative assessment of variations in sex hormone levels and echographic parameters of fertile and infertile cycles was carried out in patients with gonadotrophic deficiency during pergonal induction of the ovulation. It was demonstrated that 83% of the infertile cycles were the first stimulation cycles. Basic differences were identified in the variation of sex hormone levels and echographic parameters of target organs between the fertile and infertile cycles. It is concluded that the first ovulation-induction course should be regarded as a preventive or preparatory one, where an optimum drug dosage is adjusted while the gonads and target organs are getting ready for the ovulation.
在使用佩尔戈纳(Pergonal)诱导排卵期间,对促性腺激素缺乏患者的性激素水平变化以及有生育能力和无生育能力周期的超声参数进行了比较评估。结果表明,83%的无生育能力周期是首次刺激周期。在有生育能力和无生育能力周期之间,已确定性激素水平变化和靶器官超声参数存在基本差异。得出的结论是,首次排卵诱导疗程应被视为预防性或准备性疗程,在此期间,在性腺和靶器官为排卵做准备时调整最佳药物剂量。