van Kalleveen Irene M L, Boer Vincent O, Luijten Peter R, Klomp Dennis W J
Department of Radiology, UMC Utrecht, the Netherlands.
Magn Reson Med. 2015 Aug;74(2):482-8. doi: 10.1002/mrm.25415. Epub 2014 Aug 26.
Going to ultrahigh field MRI (e.g., 7 Tesla [T]), the nonuniformity of the B1+ field and the increased radiofrequency (RF) power deposition become challenging. While surface coils improve the power efficiency in B1+, its field remains nonuniform. In this work, an RF pulse was designed that uses the slab selection to compensate the inhomogeneous B1+ field of a surface coil without a substantial increase in specific absorption rate (SAR).
A breast surface coil was used with a decaying B1+ field in the anterior-posterior direction of the human breast. Slab selective RF pulses were designed and compared with adiabatic and spokes RF pulses. Proof of principle was demonstrated with FFE and B1+ maps of the human breast.
In vivo measurements obtained with the breast surface coil show that the tilt optimized flip uniformity (TOFU) RF pulses can improve the flip angle homogeneity by 31%, while the SAR will be lower compared with BIR-4 and spokes RF pulses.
By applying TOFU RF pulses to the breast surface coil, we are able to compensate the inhomogeneous B1+ field, while keeping the SAR low. Therefore stronger T1 -weighting in FFE sequences can be obtained, while pulse durations can remain short, as shown in the human breast at 7T.
在超高场磁共振成像(例如7特斯拉[T])中,B1+场的不均匀性以及射频(RF)功率沉积的增加成为挑战。虽然表面线圈可提高B1+中的功率效率,但其场仍不均匀。在本研究中,设计了一种射频脉冲,利用层面选择来补偿表面线圈不均匀的B1+场,而比吸收率(SAR)没有大幅增加。
使用了一个在人体乳房前后方向具有衰减B1+场的乳房表面线圈。设计了层面选择射频脉冲,并与绝热和辐条射频脉冲进行比较。通过人体乳房的快速场回波(FFE)和B1+图谱证明了原理。
使用乳房表面线圈进行的体内测量表明,倾斜优化翻转均匀性(TOFU)射频脉冲可将翻转角均匀性提高31%,同时与BIR-4和辐条射频脉冲相比,SAR会更低。
通过将TOFU射频脉冲应用于乳房表面线圈,我们能够补偿不均匀B1+场,同时保持低SAR。因此,如在7T人体乳房中所示,在FFE序列中可获得更强的T1加权,同时脉冲持续时间可保持较短。