Djarma Oumaïma, Nguyen Yohan, Renois Fanny, Djimassal Alain, Banisadr Firouze, Andreoletti Laurent
Service de Médecine interne, Hôpital Le Bon Samaritain, CHU Walia, N'Djamena, Chad.
Laboratoire de Virologie médicale et moléculaire Hôpital Robert Debré, CHU Reims & EA-4684, Faculté de Médecine, Reims, France Service de Médecine interne, Maladies infectieuses et Immunologie Clinique, Hôpital Robert Debré, CHU Reims, France.
Trans R Soc Trop Med Hyg. 2014 Nov;108(11):735-8. doi: 10.1093/trstmh/tru130. Epub 2014 Aug 26.
Retention of HAART-eligible HIV-infected patients in clinical follow-up systems are now becoming an important issue in sub-Saharan African countries.
In this retrospective study (April 2008 to November 2011), we assessed the attrition rate variations in a cohort of 509 HAART-eligible patients in Chad.
Decrease in levels of loss to follow-up were observed during the implementation of continuous free access to HAART (72.5 vs 10%; p<0.001) and was independent of gender, age, WHO clinical stage and CD4+ T cell count at inclusion and of the time delay to initiate HAART (p>0.48).
These data suggest that the implementation of free access to HAART without any interruption of supply, from autumn 2009, could be the factor that potentially changed the HIV patient attrition rate in this resource-limited setting.
在撒哈拉以南非洲国家，让符合接受高效抗逆转录病毒治疗（HAART）条件的HIV感染患者坚持临床随访正成为一个重要问题。
在这项回顾性研究（2008年4月至2011年11月）中，我们评估了乍得509例符合HAART条件患者队列中的失访率变化。
在实施持续免费提供HAART期间，观察到失访水平有所下降（72.5%对10%；p<0.001），且与性别、年龄、纳入时的世界卫生组织临床分期和CD4+T细胞计数以及开始HAART的时间延迟无关（p>0.48）。
这些数据表明，从2009年秋季开始实施不间断免费提供HAART可能是在这种资源有限环境中潜在改变HIV患者失访率的因素。
