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胰头背侧切除术:对于无法剜除的良性或低级别恶性病变,是胰十二指肠切除术的一种替代方案。

Head dorsal pancreatectomy: an alternative to the pancreaticoduodenectomy for not enucleable benign or low-grade malignant lesions.

作者信息

Iacono Calogero, Ruzzenente Andrea, Conci Simone, Xillo Laura, Guglielmi Alfredo

机构信息

Department of Surgery, Division of General Surgery A, Unit of Hepato-Pancreatico-Biliary-Surgery, University of Verona Medical School, Verona, Italy.

Department of Surgery, Division of General Surgery A, Unit of Hepato-Pancreatico-Biliary-Surgery, University of Verona Medical School, Verona, Italy.

出版信息

Pancreatology. 2014 Sep-Oct;14(5):419-24. doi: 10.1016/j.pan.2014.07.014. Epub 2014 Aug 8.

Abstract

BACKGROUND

Head dorsal pancreatectomy (HDP) is a segmental pancreatic resection, conservative variant of total dorsal pancreatectomy, applied to preserve the functional pancreatic parenchyma as an alternative to pancreaticoduodenectomy in not enucleable benign or low-grade malignant lesions. The absences of biliary and gastrointestinal resection/reconstruction are the other advantages of the technique.

METHODS

We reported a case of HDP performed in a female 39-year-old patient for a neuroendocrine tumour of the dorsal portion of the pancreatic head.

RESULTS

The superior mesenteric vein was dissected from the pancreatic neck. The pancreas was transected at the left margin of the superior mesenteric vein. After identification and mobilisation of gastroduodenal artery and the anterior superior pancreatico-duodenal artery, the head dorsal segment was dissected stepwise from the duodenal wall toward the common bile duct plane; the dissection of the pancreatic parenchyma was completed along the anterior surface of the common bile duct. An end-to-side duct-to-mucosa pancreaticojejunostomy was performed. The main pancreatic duct in the ventral segment on the dissection parenchymal surface was ligated. With the inclusion of this case, there are a total of 3 cases involving resection of the dorsal portion of the pancreatic head reported in the literature.

CONCLUSION

HDP seems to be technically feasible and safe for not enucleable benign or low-grade malignant neoplasms involving the dorsal pancreatic head. However, due to the singularity of the indications and the few cases reported in the literature, further studies are needed to validate the technique.

摘要

背景

胰头背侧切除术(HDP)是一种节段性胰腺切除术,是全胰头背侧切除术的保守术式,用于保留有功能的胰腺实质,作为无法行剜除术的良性或低级别恶性病变行胰十二指肠切除术的替代方法。该技术的其他优点是无需进行胆道和胃肠道切除/重建。

方法

我们报告了一例39岁女性患者因胰头背侧神经内分泌肿瘤接受HDP手术的病例。

结果

从胰颈处游离肠系膜上静脉。在肠系膜上静脉左侧缘横断胰腺。在识别并游离胃十二指肠动脉和胰十二指肠上前动脉后,将胰头背侧段从十二指肠壁逐步向胆总管平面分离;沿胆总管前表面完成胰腺实质的分离。行端侧胰管-黏膜胰空肠吻合术。结扎分离的胰腺实质表面腹侧段的主胰管。包括本病例在内,文献中共报道了3例涉及胰头背侧切除的病例。

结论

对于无法行剜除术的累及胰头背侧的良性或低级别恶性肿瘤,HDP在技术上似乎是可行且安全的。然而,由于适应证的特殊性以及文献报道的病例较少,需要进一步研究以验证该技术。

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