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Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.
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Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.
Cancer Prev Res (Phila). 2010 Oct;3(10):1222-34. doi: 10.1158/1940-6207.CAPR-10-0082. Epub 2010 Sep 21.
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Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas.
Cancer Prev Res (Phila). 2011 May;4(5):744-51. doi: 10.1158/1940-6207.CAPR-10-0285. Epub 2011 Mar 24.
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Murine basal cell carcinoma leads to tumor-mediated alterations in endocrine Igf1 signaling.
Endocr Relat Cancer. 2013 May 20;20(3):273-81. doi: 10.1530/ERC-12-0307. Print 2013 Jun.
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Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway.
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Clinical implications of hedgehog signaling pathway inhibitors.
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Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt.
Am J Hum Genet. 2024 Mar 7;111(3):487-508. doi: 10.1016/j.ajhg.2024.01.007. Epub 2024 Feb 6.
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UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling.
Open Med (Wars). 2023 Feb 24;18(1):20220567. doi: 10.1515/med-2022-0567. eCollection 2023.
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UBE2J1 inhibits colorectal cancer progression by promoting ubiquitination and degradation of RPS3.
Oncogene. 2023 Feb;42(9):651-664. doi: 10.1038/s41388-022-02581-7. Epub 2022 Dec 26.
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The Contributions of Cancer-Testis and Developmental Genes to the Pathogenesis of Keratinocyte Carcinomas.
Cancers (Basel). 2022 Jul 26;14(15):3630. doi: 10.3390/cancers14153630.
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How hydrolytic exoribonucleases impact human disease: Two sides of the same story.
FEBS Open Bio. 2023 Jun;13(6):957-974. doi: 10.1002/2211-5463.13392. Epub 2022 Mar 20.
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Zfx-induced upregulation of UBE2J1 facilitates endometrial cancer progression via PI3K/AKT pathway.
Cancer Biol Ther. 2021 Mar 4;22(3):238-247. doi: 10.1080/15384047.2021.1883186. Epub 2021 Feb 26.
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Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling.
Oncol Lett. 2018 Nov;16(5):6729-6734. doi: 10.3892/ol.2018.9484. Epub 2018 Sep 21.

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ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.
Cell Rep. 2014 Feb 13;6(3):528-40. doi: 10.1016/j.celrep.2014.01.007. Epub 2014 Jan 30.
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ZFX controls the self-renewal of human embryonic stem cells.
PLoS One. 2012;7(8):e42302. doi: 10.1371/journal.pone.0042302. Epub 2012 Aug 3.
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A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.
Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1377-86. doi: 10.1073/pnas.1115433109. Epub 2012 May 3.
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An animal model of MYC-driven medulloblastoma.
Cancer Cell. 2012 Feb 14;21(2):155-67. doi: 10.1016/j.ccr.2011.12.021.
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An integrated ChIP-seq analysis platform with customizable workflows.
BMC Bioinformatics. 2011 Jul 7;12:277. doi: 10.1186/1471-2105-12-277.
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Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype.
PLoS One. 2011;6(5):e20041. doi: 10.1371/journal.pone.0020041. Epub 2011 May 23.

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