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加拿大魁北克省努纳维克北欧地区肺炎球菌疫苗的接种情况。

Uptake of pneumococcal vaccines in the Nordic region of Nunavik, province of Quebec, Canada.

作者信息

Cléophat Jude-Emmanuel, Le Meur Jean-Baptiste, Proulx Jean-François, De Wals Philippe

机构信息

Université Laval.

出版信息

Can J Public Health. 2014 May 30;105(4):e268-72. doi: 10.17269/cjph.105.4315.

Abstract

OBJECTIVES

Pneumococcal infections constitute an important public health problem in Nordic regions of Canada. Nordic populations are not included in national and provincial immunization surveys and there is no centralized immunization registry in these regions. The objective of this study was to estimate pneumococcal vaccination coverage and delays in immunization of children in Nunavik, Quebec.

METHODS

Immunization records of children born in 1994-2005 were collected in all villages. Children were classified into three groups: born in the period January 1, 1994 to April 30, 1997 and targeted by the 2002 mass campaign with the 23-valent polysaccharide vaccine (PPSV23); born in the period May 1, 1997 to March 31, 2002 and targeted by the 7-valent conjugate vaccine (PCV7) catch-up campaign; born in the period April 1, 2002 to December 31, 2005 and targeted by the PCV7 routine infant program.

RESULTS

In the first group (n=896), 86.8% (95% CI: 84.4%-89.0%) were vaccinated with PPSV23. In the second group (n=1,252), 84.3% (95% CI: 82.1%-86.2%) received ≥1 PCV7 dose. In the third group, 90.4% (95% CI: 88.5%-92.1%) received 4 PCV7 doses. Delays >4 weeks in vaccine administration were observed for 26.3% of doses. There were substantial variations between villages for all indicators.

CONCLUSIONS

In the challenging setting of a Nordic and remote region, uptake rates of pneumococcal vaccines in Nunavik were found to be similar to those measured in population surveys in Quebec.

摘要

目的

肺炎球菌感染是加拿大北部地区一个重要的公共卫生问题。北部人口未被纳入国家和省级免疫调查,且这些地区没有集中的免疫登记系统。本研究的目的是估计魁北克努纳维克地区儿童的肺炎球菌疫苗接种覆盖率及免疫延迟情况。

方法

收集了所有村庄1994 - 2005年出生儿童的免疫记录。儿童被分为三组:1994年1月1日至1997年4月30日出生,以2002年23价多糖疫苗(PPSV23)大规模接种活动为目标人群;1997年5月1日至2002年3月31日出生,以7价结合疫苗(PCV7)补种活动为目标人群;2002年4月1日至2005年12月31日出生,以PCV7常规婴儿接种计划为目标人群。

结果

第一组(n = 896)中,86.8%(95%可信区间:84.4% - 89.0%)接种了PPSV23。第二组(n = 1252)中,84.3%(95%可信区间:82.1% - 86.2%)接受了≥1剂PCV7。第三组中,90.4%(95%可信区间:88.5% - 92.1%)接受了4剂PCV7。观察到26.3%的疫苗接种延迟超过4周。所有指标在不同村庄之间存在显著差异。

结论

在北部偏远地区这一具有挑战性的环境中,发现努纳维克地区肺炎球菌疫苗的接种率与魁北克省人群调查中测得的接种率相似。

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