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持续性非卧床腹膜透析(CAPD)患者的假单胞菌性腹膜炎:治疗特点与结果

Pseudomonas peritonitis in CAPD patients: characteristics and outcome of treatment.

作者信息

Chan M K, Chan P C, Cheng I P, Chan C Y, Ng W S

机构信息

Department of Medicine, University of Hong Kong.

出版信息

Nephrol Dial Transplant. 1989;4(9):814-7.

PMID:2516614
Abstract

Twenty-five episodes of Pseudomonas peritonitis which occurred over a five-and-a-half-year period were reviewed. Pseudomonas peritonitis accounted for 25/516 (4.8%) of all episodes of peritonitis. Nine of the episodes were first infections in that the patient had not experienced peritonitis before. The rest were repeat peritonitis. There was no difference in any demographic factors between the first episodes and the repeat episodes except exit site infection which was more common among patients who had repeat infections. Overall cure rate of Pseudomonas peritonitis was 20/25 (80%). Five catheters had to be removed, all in patients who had to be transferred permanently to haemodialysis. In general, ceftazidime in combination with an aminoglycoside was an effective regimen. Oral ofloxacin was not useful despite in vitro sensitivity of the pathogen to the antibiotic.

摘要

回顾了在五年半时间内发生的25例铜绿假单胞菌腹膜炎病例。铜绿假单胞菌腹膜炎占所有腹膜炎病例的25/516(4.8%)。其中9例为初次感染,即患者以前未曾经历过腹膜炎。其余为复发性腹膜炎。除出口部位感染在复发性感染患者中更常见外,初次发作和复发性发作的任何人口统计学因素均无差异。铜绿假单胞菌腹膜炎的总体治愈率为20/25(80%)。5根导管不得不被拔除,所有这些患者都必须永久转为血液透析。一般来说,头孢他啶联合氨基糖苷类是一种有效的治疗方案。尽管病原体对口服氧氟沙星在体外敏感,但口服氧氟沙星并无效果。

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