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长期阿片类药物治疗的利弊。

The pros and cons of long-term opioid therapy.

作者信息

Duarte Rui, Raphael Jon

出版信息

J Pain Palliat Care Pharmacother. 2014 Sep;28(3):308-10. doi: 10.3109/15360288.2014.943383.

Abstract

Evidence supporting the efficacy of long-term opioid therapy for chronic noncancer pain is scarce. However, weak evidence suggests that those who are able to continue opioids long-term experience clinically significant pain relief. Fear of opioid abuse or addiction should not impede the prescribing of opioids if the patients are carefully selected and monitored. In patients taking opioids who experience intolerable side effects or unsatisfactory pain relief, alternatives should be sought as soon as possible. This report is adapted from paineurope 2014; Issue 1, Haymarket Medical Publications Ltd., and is presented with permission. paineurope is provided as a service to pain management by Mundipharma International, Ltd., and is distributed free of charge to healthcare professionals in Europe. Archival issues can be accessed via the Web site: http://www.paineurope.com, at which European health professionals can register online to receive copies of the quarterly publication.

摘要

支持长期使用阿片类药物治疗慢性非癌性疼痛疗效的证据很少。然而,有微弱证据表明,那些能够长期持续使用阿片类药物的患者在临床上有显著的疼痛缓解。如果对患者进行仔细筛选和监测,对阿片类药物滥用或成瘾的担忧不应妨碍阿片类药物的处方。对于服用阿片类药物但出现无法耐受的副作用或疼痛缓解不理想的患者,应尽快寻求替代方案。本报告改编自《疼痛欧洲》2014年第1期,由海市场医疗出版有限公司出版,并经许可发布。《疼痛欧洲》由萌蒂国际有限公司提供,作为疼痛管理服务,免费分发给欧洲的医疗专业人员。过往期刊可通过网站:http://www.paineurope.com查阅,欧洲卫生专业人员可在该网站在线注册以获取季刊副本。

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