Beal Sarah J, Dorn Lorah D, Sucharew Heidi J, Sontag-Padilla Lisa, Pabst Stephanie, Hillman Jennifer
From the Cincinnati Children's Hospital Medical Center (S.J.B., H.J.S., S.P.), Cincinnati, Ohio; Pennsylvania State University (L.D.D.), State College, Pennsylvania; University of Cincinnati (S.J.B., H.J.S.), Cincinnati, Ohio; RAND Corporation (L.S.-P.), Santa Monica, California; Washington University in Saint Louis (J.H.), St. Louis, Missouri.
Psychosom Med. 2014 Sep;76(7):547-54. doi: 10.1097/PSY.0000000000000099.
This study examined the association between depressive and menstrual symptoms in adolescent girls in a 3-year longitudinal study. It was hypothesized that menstrual symptoms would increase in early adolescence and decrease in later adolescence, that girls with greater depressive symptoms would report greater menstrual symptoms, and that effects would persist after adjusting for general somatic complaints.
A community sample of girls (n = 262) enrolled in an observational study by age cohort (11, 13, 15, 17 years) completed three annual visits. At each time point, girls completed the Menstrual Symptom Questionnaire, Children's Depression Inventory, and the Youth Self Report to assess general somatic complaints.
Menstrual symptoms increased significantly across adolescence (p = .006) and began to plateau in later adolescence (p = .020). Depressive symptoms at study entry were significantly associated with menstrual symptoms (p < .001). When general somatic complaints were included in the models, the effect of depressive symptoms on menstrual symptoms remained significant for the sum score (p = .015) and the menstrual somatic symptoms subscale (p = .001). After adjusting for somatic complaints, initial report of depressive symptoms predicted change in menstrual symptoms only for girls with the lowest menstrual symptoms sum score (p = .025). Initial report of somatic complaints predicted change in menstrual symptoms (p = .020).
Girls with higher depressive symptoms and higher somatic complaints are at greater risk for experiencing menstrual symptoms and increasing symptoms across adolescence, with a heightened vulnerability for girls with lower baseline menstrual symptoms.
本研究通过一项为期3年的纵向研究,考察了青春期女孩抑郁症状与月经症状之间的关联。研究假设为,月经症状在青春期早期会增加,在青春期后期会减少;抑郁症状较重的女孩会报告更严重的月经症状;在对一般躯体不适进行调整后,这些影响仍会持续存在。
一个按年龄队列(11、13、15、17岁)纳入观察性研究的社区女孩样本(n = 262)完成了三次年度随访。在每个时间点,女孩们完成了月经症状问卷、儿童抑郁量表和青少年自我报告,以评估一般躯体不适。
月经症状在整个青春期显著增加(p = .006),并在青春期后期开始趋于平稳(p = .020)。研究开始时的抑郁症状与月经症状显著相关(p < .001)。当在模型中纳入一般躯体不适时,抑郁症状对月经症状总分(p = .015)和月经躯体症状子量表(p = .001)的影响仍然显著。在对躯体不适进行调整后,抑郁症状的初始报告仅对月经症状总分最低的女孩预测月经症状的变化有意义(p = .025)。躯体不适的初始报告预测月经症状的变化(p = .020)。
抑郁症状较高和躯体不适较高的女孩在青春期出现月经症状和症状加重的风险更大,基线月经症状较低的女孩更易出现这种情况。