Simal-Julián Juan A, Miranda-Lloret Pablo, Evangelista-Zamora Rocio, Sanromán-Álvarez Pablo, Pérez de San Román Laila, Pérez-Borredá Pedro, Beltrán-Giner Andrés, Botella-Asunción Carlos
Neurosurgical Department, HUyP La Fe de Valencia, Blv Sur, S/N, Valencia, Spain,
Neurosurg Rev. 2015 Jan;38(1):49-57; discussion 57. doi: 10.1007/s10143-014-0570-6. Epub 2014 Aug 30.
Indocyanine green videoangiography (ICGVA) procedures have become widespread within the spectrum of microsurgical techniques for neurovascular pathologies. We have conducted a review to identify and assess the impact of all of the methodological variations of conventional ICGVA applied in the field of neurovascular pathology that have been published to date in the English literature. A total of 18 studies were included in this review, identifying four primary methodological variants compared to conventional ICGVA: techniques based on the transient occlusion, intra-arterial ICG administration via catheters, use of endoscope system with a filter to collect florescence of ICG, and quantitative fluorescence analysis. These variants offer some possibilities for resolving the limitations of the conventional technique (first, the vascular structure to be analyzed must be exposed and second, vascular filling with ICG follows an additive pattern) and allow qualitatively superior information to be obtained during surgery. Advantages and disadvantages of each procedure are discussed. More case studies with a greater number of patients are needed to compare the different procedures with their gold standard, in order to establish these results consistently.
吲哚菁绿视频血管造影术（ICGVA）在神经血管疾病的显微外科技术领域已广泛应用。我们进行了一项综述，以识别和评估迄今为止英文文献中发表的、应用于神经血管疾病领域的传统ICGVA所有方法学变体的影响。本综述共纳入18项研究，确定了与传统ICGVA相比的四种主要方法学变体：基于短暂闭塞的技术、通过导管进行动脉内ICG给药、使用带有滤光片的内窥镜系统收集ICG荧光以及定量荧光分析。这些变体为解决传统技术的局限性（首先，必须暴露要分析的血管结构；其次，ICG血管充盈呈累加模式）提供了一些可能性，并能在手术期间获得质量上更优的信息。讨论了每种方法的优缺点。需要更多包含更多患者的病例研究，将不同方法与其金标准进行比较，以便一致地确立这些结果。
