Komatsu Ryu, Dalton Jarrod E, Ghobrial Michael, Fu Alexander Y, Lee Jae H, Egan Cameron, Sessler Daniel I, Kasuya Yusuke, Turan Alparslan
Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Ave.,/E30, Cleveland, OH, 44195 USA.
Department of Quantitative Health Sciences, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA; Department of OUTCOMES RESEARCH, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
J Clin Anesth. 2014 Sep;26(6):432-7. doi: 10.1016/j.jclinane.2014.01.019. Epub 2014 Aug 27.
To investigate whether Type O blood group status is associated with increased intraoperative blood loss and requirement of blood transfusion in extensive spine surgery.
Retrospective comparative study.
University-affiliated, non-profit teaching hospital.
Data from 1,050 ASA physical status 1, 2, 3, 4, and 5 patients who underwent spine surgeries involving 4 or more vertebral levels were analyzed. Patients with Type O blood were matched to similar patients with other blood types using propensity scores, which were estimated via demographic and morphometric data, medical history variables, and extent of surgery. Intraoperative estimated blood loss (EBL) was compared among matched patients using a linear regression model; intraoperative transfusion requirement in volume of red blood cells, fresh frozen plasma, platelet, cryoprecipitate, cell salvaged blood, volume of intraoperative infusion of hetastarch, 5% albumin, crystalloids, and hospital length of hospital (LOS) were compared using Wilcoxon rank-sum tests.
Intraoperative EBL and requirement of blood product transfusion were similar in patients with Type O blood group and those with other blood groups.
There was no association between Type O blood and increased intraoperative blood loss or blood transfusion requirement during extensive spine surgery, with similar hospital LOS in Type O and non-O patients.
探讨在广泛脊柱手术中,O型血状态是否与术中失血量增加及输血需求有关。
回顾性比较研究。
大学附属非营利性教学医院。
分析了1050例美国麻醉医师协会(ASA)身体状况为1、2、3、4和5级且接受涉及4个或更多椎体节段脊柱手术患者的数据。利用倾向评分将O型血患者与其他血型的类似患者进行匹配,倾向评分通过人口统计学和形态学数据、病史变量以及手术范围进行估算。使用线性回归模型比较匹配患者之间的术中估计失血量(EBL);使用Wilcoxon秩和检验比较红细胞、新鲜冰冻血浆、血小板、冷沉淀、回收血的术中输血量、羟乙基淀粉、5%白蛋白、晶体液的术中输注量以及住院时间(LOS)。
O型血患者与其他血型患者的术中EBL及血液制品输血需求相似。
在广泛脊柱手术中O型血与术中失血量增加或输血需求增加之间无关联,O型血患者与非O型血患者的住院时间相似。