Schoepke N, Młynek A, Weller K, Church M K, Maurer M
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin, Berlin, Germany.
J Eur Acad Dermatol Venereol. 2015 Apr;29(4):708-12. doi: 10.1111/jdv.12661. Epub 2014 Aug 29.
Symptomatic dermographism is the most common form of physical urticaria with a prevalence of 2-5%. However, its clinical picture has rarely been described.
To understand more of patients' views about the practical aspects of their condition, its cause and impact on quality of life.
Ninety-one of 150 patients with symptomatic dermographism from our specialist urticaria clinic completed a 38-question questionnaire sent them by mail.
The mean duration of disease was 6¼ years. In most patients, the condition was continuous, but ~25% had prolonged symptom-free phases. Severity was evaluated as moderate in 45%, severe in 33% and very severe in 6% of respondents. Other responses included: symptoms worse in the evening in 81%; quality of life significantly impaired in 44%; normal life not possible 7%; stress induces acute episodes 44%; other urticarial forms coexist 21%; allergy coexist 48%. A family history was reported in 14%. Almost all patients were taking H1 -anti-histamines, 49% getting marked improvement and 23% becoming symptoms free.
It is a survey only of patient opinions.
This questionnaire survey confirmed that symptomatic dermographism is a debilitating condition with profound effects on quality of life but its underlying cause and disease mechanisms remain obscure.
症状性皮肤划痕症是物理性荨麻疹最常见的形式，患病率为2%-5%。然而，其临床表现鲜有描述。
更深入了解患者对自身病情实际情况、病因及其对生活质量影响的看法。
我们专科荨麻疹诊所的150例症状性皮肤划痕症患者中有91例完成了通过邮件发送给他们的一份包含38个问题的调查问卷。
疾病的平均持续时间为6¼年。大多数患者病情呈持续性，但约25%有症状缓解期延长的情况。45%的受访者将严重程度评估为中度，33%为重度，6%为极重度。其他反馈包括：81%的患者晚上症状更严重；44%的患者生活质量受到显著损害；7%的患者无法正常生活；44%的患者压力会诱发急性发作；21%的患者同时存在其他荨麻疹形式；48%的患者同时存在过敏。14%的患者有家族病史。几乎所有患者都在服用H1抗组胺药，49%的患者有明显改善，23%的患者症状消失。
这只是一项关于患者意见的调查。
这项问卷调查证实，症状性皮肤划痕症是一种使人衰弱的疾病，对生活质量有深远影响，但其根本原因和发病机制仍不清楚。
