Sasnur Prasad, Nidoni Ravindra, Baloorkar Ramakanth, Sindgikar Vikram, Shankar Bharat
Assistant Professor, Department of General Surgery, BLDEU's Shri. B. M. Patil Medical College , Bijapur, Karnataka, India .
Senior Resident, Department of General Surgery, BLDEU's Shri. B. M. Patil Medical College , Bijapur, Karnataka, India .
J Clin Diagn Res. 2014 Jul;8(7):NR01-2. doi: 10.7860/JCDR/2013/8196.4600. Epub 2014 Jul 20.
The treatment of infected necrotizing pancreatitis has evolved from time to time and the success of surgical intervention depends on the timing of necrosectomy. Bacterial infection occurs in 40-70% of patients with necrotizing pancreatitis. Infection is the main risk factor for mortality among patients with pancreatic necrosis. Timely intervention is generally required for pancreatic necrosis but is now deferred until four weeks after disease onset in order to permit encapsulation and demarcation of the necrotic material. Demarcation facilitates necrosectomy and reduces complications related to the drainage and debridement procedures. The approach to pancreatic necrosectomy has evolved from primary open necrosectomy to minimally-invasive radiologic, surgical and endoscopic procedures. Direct endoscopic necrosectomy is a minimally-invasive technique that was introduced in recent years for the treatment of walled-off necrosis. The pancreas is approached through the posterior wall of stomach and debridement is done.
感染性坏死性胰腺炎的治疗方法一直在不断演变,手术干预的成功与否取决于坏死组织清除术的时机。40%至70%的坏死性胰腺炎患者会发生细菌感染。感染是胰腺坏死患者死亡的主要危险因素。胰腺坏死通常需要及时干预,但现在推迟到发病四周后进行,以便坏死物质能够包裹和分界。分界有利于坏死组织清除术,并减少与引流和清创手术相关的并发症。胰腺坏死组织清除术的方法已从最初的开放性坏死组织清除术发展为微创放射学、外科和内镜手术。直接内镜坏死组织清除术是近年来引入的一种微创技术,用于治疗包裹性坏死。通过胃后壁进入胰腺并进行清创。