Liebhart M
Patol Pol. 1989;40(2):159-69.
We studied 17 cases of deep fascicular fibromatoses of various location in children and adolescents from 7 months to 16 years. Basic proliferative cells consisted of mature cells of the connective tissue slightly changed cytologic features but without atypia. We observed scanty regular mitoses. Histological structure of individual tumours and fields in the same tumours differed in the degree of collagenization, vascularization and abundance of cells. In four cases proliferations were differentiated with neurofibromatosis, in one case with fibrosarcoma of high-degree differentiation. In four cases the tumours were of desmoid structure. In two cases of mesenteric location of the proliferation we found foci of cartilagous metaplasia, which in one case after several recurrences transformed the tumour into a chondrosarcoma.
我们研究了17例7个月至16岁儿童及青少年不同部位的深部束状纤维瘤病。基本增殖细胞由结缔组织的成熟细胞组成，其细胞学特征略有改变但无异型性。我们观察到少量规则的有丝分裂。单个肿瘤及同一肿瘤内不同区域的组织结构在胶原化程度、血管化程度和细胞丰度方面存在差异。4例增殖性病变与神经纤维瘤病相鉴别，1例与高分化纤维肉瘤相鉴别。4例肿瘤呈硬纤维瘤结构。在2例增殖性病变位于肠系膜的病例中，我们发现了软骨化生灶，其中1例在多次复发后肿瘤转变为软骨肉瘤。
