Coco J W, Pankey G A
Compendium. 1989 Dec;10(12):664-8, 670-2.
The use of antimicrobials in dentistry parallels their use in medical outpatient settings. The emphasis is on patient safety rather than on the agent efficacy. Some antimicrobials should never be used as initial therapy for outpatients in dentistry or medicine. These agents carry an unacceptably high risk of adverse effects and, for use in infections that do not require hospitalization, there are adequate substitutes. Some antimicrobials should only be used infrequently, and there are a few that are recommended for extensive use. Since the initial article was published in The Compendium in 1980, a few significant advances have occurred. This article will cover these advances and will review three groups of antimicrobials, describing salient characteristics, adverse reactions, and prescribing recommendations.
牙科领域抗菌药物的使用与医学门诊环境中的使用情况相似。重点在于患者安全而非药物疗效。某些抗菌药物绝不应用于牙科或医学门诊患者的初始治疗。这些药物具有高得不可接受的不良反应风险，并且对于不需要住院治疗的感染，有足够的替代药物。某些抗菌药物应仅偶尔使用，还有少数几种推荐广泛使用。自1980年最初的文章发表于《概要》以来，已取得了一些重大进展。本文将涵盖这些进展，并将回顾三类抗菌药物，描述其显著特征、不良反应及用药建议。
