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新南威尔士州2型糖尿病患者的用药行为:一项观察性研究。

Medication-taking behaviour in New South Wales patients with type 2 diabetes: an observational study.

作者信息

Dhippayom Teerapon, Krass Ines

出版信息

Aust J Prim Health. 2015;21(4):429-37. doi: 10.1071/PY14062.

Abstract

This study aimed to (1) determine adherence to diabetes medication in type 2 diabetes (T2D) patients; (2) describe respondents' attitudes and beliefs about medications, and barriers to adherence; and (3) to model predictors of non-adherence. Data were collected using online and postal surveys. Diabetes patients aged 18 years who were members of the Australian Diabetes Council were invited to participate. Main outcome measures were adherence to diabetes medication using 8-item Morisky Medication Adherence Score (MMAS-8) and beliefs about medication using the Beliefs about Medicines Questionnaire. A total of 543 T2D patients responded to the survey. The median (interquartile range) MMAS-8 score was 6.8 (5.0-7.0). The prevalence of adherence (MMAS-8 score 6) was 64.6%. The proportion of respondents who expressed concern about taking medications was 53.6%. Potential predictors of adherence included age (OR, 1.83; 95% CI, 1.19-2.82), concern about medication (OR, 0.91; 95% CI, 0.87-0.96), knowledge of diabetes (OR, 0.85, 95% CI, 0.73-0.99), having difficulty in paying for medication (OR, 0.51; 95% CI, 0.33-0.79), having more than one regular pharmacy (OR, 0.59; 95% CI, 0.36-0.95), and using insulin (OR, 0.49; 95% CI, 0.30-0.81). Adherence to taking diabetes medication in a sample of the Australian T2D patient population was suboptimal. An understanding of medication-taking behaviour will assist health-care professionals to deliver appropriate and effective interventions to enhance adherence and optimise diabetes control in T2D patients.

摘要

本研究旨在

(1)确定2型糖尿病(T2D)患者对糖尿病药物的依从性;(2)描述受访者对药物的态度和信念以及依从性的障碍;(3)建立不依从的预测模型。通过在线和邮寄调查收集数据。邀请了年龄在18岁及以上、身为澳大利亚糖尿病协会成员的糖尿病患者参与。主要结局指标包括使用8项Morisky药物依从性量表(MMAS-8)评估的糖尿病药物依从性,以及使用药物信念问卷评估的对药物的信念。共有543名T2D患者回复了调查。MMAS-8评分的中位数(四分位间距)为6.8(5.0 - 7.0)。依从性(MMAS-8评分≥6)的患病率为64.6%。表示担心服药的受访者比例为53.6%。依从性的潜在预测因素包括年龄(比值比[OR],1.83;95%置信区间[CI],1.19 - 2.82)、对药物的担心(OR,0.91;95%CI,0.87 - 0.96)、糖尿病知识(OR,0.85;95%CI,0.73 - 0.99)、支付药费困难(OR,0.51;95%CI,0.33 - 0.79)、有不止一家常规药房(OR,0.59;95%CI,0.36 - 0.95)以及使用胰岛素(OR,0.49;95%CI,0.30 - 0.81)。在澳大利亚T2D患者样本中,糖尿病药物的服药依从性欠佳。了解服药行为将有助于医护人员提供恰当且有效的干预措施,以提高依从性并优化T2D患者的糖尿病控制。

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